frmB:Quickview: Difference between revisions

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!align=left |Standard Name
!align=left {{table_heading_style}} |Standard Name
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''frmB''  
''frmB''  
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!align=left |Gene Synonym(s)
!align=left {{table_heading_style}} |Gene Synonym(s)
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''ECK0352, b0355, JW0346, yaiM''<ref name='LIB:Riley_2006'/>
''ECK0352, b0355, JW0346, yaiM''<ref name='LIB:Riley_2006'/>
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!align=left |Product Desc.
!align=left {{table_heading_style}} |Product Desc.
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<i>S</i>-formylglutathione hydrolase<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
<i>S</i>-formylglutathione hydrolase<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
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S-formylglutathione hydrolase, formaldehyde degradation<ref name='LIB:EcoGene'/>
S-formylglutathione hydrolase, formaldehyde degradation<ref name='LIB:EcoGene'/>
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!align=left |Product Synonyms(s)
!align=left {{table_heading_style}} |Product Synonyms(s)
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predicted esterase<ref name='LIB:Riley_2006'/>, B0355<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YaiM<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, FrmB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
predicted esterase<ref name='LIB:Riley_2006'/>, B0355<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YaiM<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, FrmB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
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!align=left |Knock-Out Phenotype
!align=left {{table_heading_style}} |Function from GO
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!align=left |Regulation/Expression
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:frmB|frmB]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:frmB|frmB]]<ref name='LIB:EcoCyc10.6'/>  
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!align=left |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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!align=left {{table_heading_style}} |Quick Links
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[http://ecoliwiki.net/tools/display_dna.php?gene=frmB&loc=MG1655:377592..376759,W3110:377592..376759,DH10B:316923..316090,REL606:350726..349893 DNA display]&nbsp;&nbsp;&nbsp; [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=350726&end=349893&gene=frmB&aa=meliekhvsfggwqnmyrhysqslkcemnvgvylppkaaneklpvlywlsgltcneqnfitksgmqryaaehniivvapdtsprgshvadadrydlgqgagfylnatqapwnehykmydyirnelpdlvmhhfpatakksisghsmgglgalvlalrnpdeyvsvsafspivspsqvpwgqqafaaylaenkdawldydpvslisqgqrvaeimvdqglsddfyaeqlrtpnlekicqemniktliryhegydhsyyfvssfigehiayhanklnmr Protein display]&nbsp;&nbsp;&nbsp; [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=frmB+AND+escherichia+coli Pubmed(frmB)]&nbsp;&nbsp;&nbsp; [http://trimer.tamu.edu/cgi-bin/textpresso/2.1/ecoli/search?searchstring=frmB Textpresso(frmB)]


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Revision as of 23:58, 21 January 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

frmB

Gene Synonym(s)

ECK0352, b0355, JW0346, yaiM[1]

Product Desc.

S-formylglutathione hydrolase[2][3]

S-formylglutathione hydrolase, formaldehyde degradation[4]

Product Synonyms(s)

predicted esterase[1], B0355[2][1], YaiM[2][1], FrmB[2][1]

Function from GO
Knock-Out Phenotype
Regulation/Expression

transcription unit(s): frmB[2]

Regulation/Activity
Quick Links

DNA display    Protein display    Pubmed(frmB)    Textpresso(frmB)

See Help:Quickview for help with entering information in the Quickview table.

Notes

[back to top]


FrmB also has p-nitrophenyl C2-C6 fatty acid ester and a-naphthyl acetate carboxylesterase activities in vitro. The frmRAB operon is negatively regulated by frmR, is induced by formaldehyde, and probably degrades formaldehyde. FrmB is 50% identical to P. denitrificans S-formylglutathione hydrolase. FrmB and YeiG are 50% identical paralogs; double mutant is formaldehyde sensitive; this may explain why an frmB single mutant did not have a formadehyde phenotype when tested on Biolog plates (Herring, 2004). The amino terminal half of FrmB is homologus to the C-terminal half of YieL. S9 peptidase family; YeiG or FrmB are not in MEROPS yet, but it has homologs.[4]



References

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  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.