mltB:Quickview: Difference between revisions

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!align=left |Standard Name
!align=left {{table_heading_style}} |Standard Name
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''mltB''  
''mltB''  
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!align=left |Gene Synonym(s)
!align=left {{table_heading_style}} |Gene Synonym(s)
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''ECK2696, b2701, JW2671''<ref name='LIB:Riley_2006'/>
''ECK2696, b2701, JW2671''<ref name='LIB:Riley_2006'/>
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!align=left |Product Desc.
!align=left {{table_heading_style}} |Product Desc.
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membrane-bound lytic murein transglycosylase B<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
membrane-bound lytic murein transglycosylase B<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
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Membrane-bound lytic transglycosylase B, murein hydrolase; periplasmic OM-attached lipoprotein; Slt35, soluble lytic transglycosylase<ref name='LIB:EcoGene'/>
Membrane-bound lytic transglycosylase B, murein hydrolase; periplasmic OM-attached lipoprotein; Slt35, soluble lytic transglycosylase<ref name='LIB:EcoGene'/>
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!align=left |Product Synonyms(s)
!align=left {{table_heading_style}} |Product Synonyms(s)
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membrane-bound lytic murein transglycosylase B<ref name='LIB:Riley_2006'/>, B2701<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, MltB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
membrane-bound lytic murein transglycosylase B<ref name='LIB:Riley_2006'/>, B2701<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, MltB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
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!align=left |Knock-Out Phenotype
!align=left {{table_heading_style}} |Function from GO
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'''Biological Process'''
* GO:0000910 cytokinesis ([http://www.geneontology.org/GO.evidence.shtml IGI])
* GO:0009252 peptidoglycan biosynthetic process ([http://www.geneontology.org/GO.evidence.shtml IMP])
'''Molecular Function'''
* GO:0008933 lytic transglycosylase activity ([http://www.geneontology.org/GO.evidence.shtml IMP])


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!align=left |Regulation/Expression
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:mltB|mltB]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:mltB|mltB]]<ref name='LIB:EcoCyc10.6'/>  
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!align=left |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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!align=left {{table_heading_style}} |Quick Links
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[http://ecoliwiki.net/tools/display_dna.php?gene=mltB&loc=MG1655:2823598..2822513,W3110:2824232..2823147,REL606:2720435..2719350,DH10B:2916140..2915055 DNA display]&nbsp;&nbsp;&nbsp; [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=2916140&end=2915055&gene=mltB&aa=mfkrryvtllplfvllaacsskpkptetdtttgtpsggfllepqhnvmqmggdfannpnaqqfidkmvnkhgfdrqqlqeilsqakrldsvlrlmdnqapttsvkppsgpngawlryrkkfitpdnvqngvvfwnqyedalnrawqvygvppeiivgiigvetrwgrvmgktrildalatlsfnyprraeyfsgeletfllmardeqddplnlkgsfagamgygqfmpssykqyavdfsgdghinlwdpvdaigsvanyfkahgwvkgdqvavmangqapglpngfktkysisqlaaagltpqqplgnhqqasllrldvgtgyqywyglpnfytitrynhsthyamavwqlgqavalarvq Protein display]&nbsp;&nbsp;&nbsp; [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=mltB+AND+escherichia+coli Pubmed(mltB)]&nbsp;&nbsp;&nbsp; [http://trimer.tamu.edu/cgi-bin/textpresso/2.1/ecoli/search?searchstring=mltB Textpresso(mltB)]


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Revision as of 23:43, 21 January 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

mltB

Gene Synonym(s)

ECK2696, b2701, JW2671[1]

Product Desc.

membrane-bound lytic murein transglycosylase B[2][3]

Membrane-bound lytic transglycosylase B, murein hydrolase; periplasmic OM-attached lipoprotein; Slt35, soluble lytic transglycosylase[4]

Product Synonyms(s)

membrane-bound lytic murein transglycosylase B[1], B2701[2][1], MltB[2][1]

Function from GO

Biological Process

Molecular Function

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): mltB[2]

Regulation/Activity
Quick Links

DNA display    Protein display    Pubmed(mltB)    Textpresso(mltB)

See Help:Quickview for help with entering information in the Quickview table.

Notes

[back to top]


MltB cleaves the glycosidic bonds between the N-acetylmuramic acid and N-acetylglucosamine residues in murein. Slt35 is a soluble form of MltB with the lipid-anchored N-terminus cleaved after Phe39 during purification. The N-terminus of Slt35 has been identified by protein sequencing, but Slt35 is is an artifact of proteolysis during purification. First 18 aa are a type II signal peptide.[4]



References

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  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.