pdhR:Quickview: Difference between revisions

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!align=left |Standard Name
!align=left {{table_heading_style}} |Standard Name
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''pdhR''  
''pdhR''  
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!align=left |Gene Synonym(s)
!align=left {{table_heading_style}} |Gene Synonym(s)
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''ECK0112, b0113, JW0109, yacB, aceC, genA, dcuA'''<ref name='LIB:Riley_2006'/><ref name='LIB:EcoCyc10.6'/>
''ECK0112, b0113, JW0109, yacB, aceC, genA, dcuA'''<ref name='LIB:Riley_2006'/><ref name='LIB:EcoCyc10.6'/>
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!align=left |Product Desc.
!align=left {{table_heading_style}} |Product Desc.
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PdhR transcriptional dual regulator<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
PdhR transcriptional dual regulator<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
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Pyruvate dehydrogenase operon (pdhR-aceEF-lpd) repressor; autoregulatory; pyruvate relieves repression; monomeric<ref name='LIB:EcoGene'/>
Pyruvate dehydrogenase operon (pdhR-aceEF-lpd) repressor; autoregulatory; pyruvate relieves repression; monomeric<ref name='LIB:EcoGene'/>
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!align=left |Product Synonyms(s)
!align=left {{table_heading_style}} |Product Synonyms(s)
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DNA-binding transcriptional dual regulator<ref name='LIB:Riley_2006'/>, B0113<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YacB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, GenA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, PdhR<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
DNA-binding transcriptional dual regulator<ref name='LIB:Riley_2006'/>, B0113<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YacB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, GenA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, PdhR<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
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!align=left |Knock-Out Phenotype
!align=left {{table_heading_style}} |Function from GO
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'''Biological Process'''
* GO:0006350 transcription ([http://www.geneontology.org/GO.evidence.shtml IDA,IEP])
'''Molecular Function'''
* GO:0016564 transcription repressor activity ([http://www.geneontology.org/GO.evidence.shtml IDA,IEP])


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!align=left |Regulation/Expression
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:pdhR-aceEF-lpdA|pdhR-aceEF-lpdA]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:pdhR-aceEF-lpdA|pdhR-aceEF-lpdA]]<ref name='LIB:EcoCyc10.6'/>  
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!align=left |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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!align=left {{table_heading_style}} |Quick Links
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[http://ecoliwiki.net/tools/display_dna.php?gene=pdhR&loc=MG1655:122092..122856,W3110:122092..122856,DH10B:96196..96960,REL606:124896..125660 DNA display]&nbsp;&nbsp;&nbsp; [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=124896&end=125660&gene=pdhR&aa=mayskirqpklsdvieqqleflilegtlrpgeklpperelakqfdvsrpslreaiqrleakglllrrqgggtfvqsslwqsfsdplvellsdhpesqydlletrhalegiaayyaalrstdedkerirelhhaielaqqsgdldaesnavlqyqiavteaahnvvllhllrcmepmlaqnvrqnfellysrremlplvsshrtrifeaimagkpeeareashrhlafieeilldrsreesrrerslrrleqrkn Protein display]&nbsp;&nbsp;&nbsp; [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=pdhR+AND+escherichia+coli Pubmed(pdhR)]&nbsp;&nbsp;&nbsp; [http://trimer.tamu.edu/cgi-bin/textpresso/2.1/ecoli/search?searchstring=pdhR Textpresso(pdhR)]


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Revision as of 23:36, 21 January 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

pdhR

Gene Synonym(s)

ECK0112, b0113, JW0109, yacB, aceC, genA, dcuA'[1][2]

Product Desc.

PdhR transcriptional dual regulator[2][3]

Pyruvate dehydrogenase operon (pdhR-aceEF-lpd) repressor; autoregulatory; pyruvate relieves repression; monomeric[4]

Product Synonyms(s)

DNA-binding transcriptional dual regulator[1], B0113[2][1], YacB[2][1], GenA[2][1], PdhR[2][1]

Function from GO

Biological Process

Molecular Function

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): pdhR-aceEF-lpdA[2]

Regulation/Activity
Quick Links

DNA display    Protein display    Pubmed(pdhR)    Textpresso(pdhR)

See Help:Quickview for help with entering information in the Quickview table.

Notes

[back to top]


The N-terminus of overexpressed PdhR has been determined (Quail and Guest, 1995), indicating that the initial Met is removed. however, the native pdhR RBS was not used, so PdhR is not in the Verified Set, although this is probably the correct start. PdhR is a GntR-type DNA-binding transcriptional regulator.[4]



References

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  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.