plsY:Quickview: Difference between revisions

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!align=left {{table_heading_style}} |Standard Name
!align=left |Standard Name
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''plsY''  
''plsY''  
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!align=left {{table_heading_style}} |Gene Synonym(s)
!align=left |Gene Synonym(s)
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''ECK3049, b3059, JW3031''<ref name='LIB:Riley_2006'/>, ygiH product
''ECK3049, b3059, JW3031''<ref name='LIB:Riley_2006'/>, ygiH product
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!align=left {{table_heading_style}} |Product Desc.
!align=left |Product Desc.
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conserved inner membrane protein<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
conserved inner membrane protein<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
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Probable acylphosphate:glycerol-3-phosphate acyltransferase<ref name='LIB:EcoGene'/>
Probable acylphosphate:glycerol-3-phosphate acyltransferase<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Product Synonyms(s)
!align=left |Product Synonyms(s)
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conserved inner membrane protein<ref name='LIB:Riley_2006'/>, B3059<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YgiH<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
conserved inner membrane protein<ref name='LIB:Riley_2006'/>, B3059<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YgiH<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
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!align=left {{table_heading_style}} |Knock-Out Phenotype
!align=left |Knock-Out Phenotype
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!align=left {{table_heading_style}} |Regulation/Expression
!align=left |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:plsY|plsY]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:plsY|plsY]]<ref name='LIB:EcoCyc10.6'/>  
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!align=left {{table_heading_style}} |Regulation/Activity
!align=left |Regulation/Activity
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Revision as of 02:19, 10 January 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

plsY

Gene Synonym(s)

ECK3049, b3059, JW3031[1], ygiH product

Product Desc.

conserved inner membrane protein[2][3]

Probable acylphosphate:glycerol-3-phosphate acyltransferase[4]

Product Synonyms(s)

conserved inner membrane protein[1], B3059[2][1], YgiH[2][1]

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): plsY[2]

Regulation/Activity


edit table

See Help:Quickview for help with entering information in the Quickview table.

Notes

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ygiH(plsY) and plsX are synthetic lethals and cannot be simultaneously deleted, implicating ygiH(plsY) involvement in phospholipid biosynthesis (Yoshimura, 2007). Homologous to the PlsY acylphosphate:glycerol-3-phosphate acyltransferase (UniProt: P0A4Q0) of S. pneumoniae, which identifies a function for the UPF0078 family (COG0344). S. pneumoniae PlsX and PlsY work together as a two-step glycerol-3-phosphate acylation, the first step in phosphatidic acid synthesis, an intermediate in phospholipid synthesis (Lu, 2006). PlsXY homologs are present in E. coli, but PlsXY apparently cannot substitute for the single step reaction catalyzed by PlsB, which is essental in E. coli.[4]



References

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  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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