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!align=left |Standard Name
!align=left {{table_heading_style}} |Standard Name
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''nuoM''  
''nuoM''  
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!align=left |Gene Synonym(s)
!align=left {{table_heading_style}} |Gene Synonym(s)
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''ECK2271, b2277, JW2272''<ref name='LIB:Riley_2006'/>
''ECK2271, b2277, JW2272''<ref name='LIB:Riley_2006'/>
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!align=left |Product Desc.
!align=left {{table_heading_style}} |Product Desc.
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NuoM<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;  
NuoM<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;  
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NADH:ubiquinone oxidoreductase subunit M, complex I; contains the ubiquinone-binding site, is homologus to antiporters, and is implicated in proton pumping<ref name='LIB:EcoGene'/>
NADH:ubiquinone oxidoreductase subunit M, complex I; contains the ubiquinone-binding site, is homologus to antiporters, and is implicated in proton pumping<ref name='LIB:EcoGene'/>
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!align=left |Product Synonyms(s)
!align=left {{table_heading_style}} |Product Synonyms(s)
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NADH:ubiquinone oxidoreductase, membrane subunit M<ref name='LIB:Riley_2006'/>, B2277<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, NuoM<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
NADH:ubiquinone oxidoreductase, membrane subunit M<ref name='LIB:Riley_2006'/>, B2277<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, NuoM<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
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!align=left |Knock-Out Phenotype
!align=left {{table_heading_style}} |Function from GO
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'''Cellular Component'''
* GO:0005886 plasma membrane ([http://www.geneontology.org/GO.evidence.shtml IDA])
* GO:0005887 integral to plasma membrane ([http://www.geneontology.org/GO.evidence.shtml IDA])
* GO:0030964 NADH dehydrogenase complex ([http://www.geneontology.org/GO.evidence.shtml IDA])
* GO:0045272 plasma membrane respiratory chain complex I ([http://www.geneontology.org/GO.evidence.shtml IDA])
'''Biological Process'''
* GO:0009060 aerobic respiration ([http://www.geneontology.org/GO.evidence.shtml IMP])
* GO:0009061 anaerobic respiration ([http://www.geneontology.org/GO.evidence.shtml IMP])
* GO:0015990 electron transport coupled proton transport ([http://www.geneontology.org/GO.evidence.shtml IMP])
'''Molecular Function'''
* GO:0015453 oxidoreduction-driven active transmembrane transporter activity ([http://www.geneontology.org/GO.evidence.shtml IDA])
* GO:0048039 ubiquinone binding ([http://www.geneontology.org/GO.evidence.shtml IDA])
* GO:0003954 NADH dehydrogenase activity ([http://www.geneontology.org/GO.evidence.shtml IDA])


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!align=left |Regulation/Expression
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:nuoABCEFGHIJKLMN|nuoABCEFGHIJKLMN]]<ref name='LIB:EcoCyc10.6'/>, nuo1-14  
transcription unit(s): [[:Category:Txn_unit:nuoABCEFGHIJKLMN|nuoABCEFGHIJKLMN]]<ref name='LIB:EcoCyc10.6'/>, nuo1-14  
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!align=left |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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!align=left {{table_heading_style}} |Quick Links
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[http://ecoliwiki.net/tools/display_dna.php?gene=nuoM&loc=MG1655:2391063..2389534,W3110:2397711..2396182,DH10B:2482828..2481299,REL606:2336565..2335036 DNA display]&nbsp;&nbsp;&nbsp; [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=2336565&end=2335036&gene=nuoM&aa=mllpwlilipfiggflcwqterfgvkvprwialitmgltlalslqlwlqggysltqsagipqwqsefdmpwiprfgisihlaidglsllmvvltgllgvlavlcswkeiekyqgffhlnlmwilggvigvflaidmflffffwemmlvpmyflialwghkasdgktritaatkffiytqasglvmliailalvfvhynatgvwtfnyeellntpmssgveyllmlgffiafavkmpvvplhgwlpdahsqaptagsvdlagillktaaygllrfslplfpnasaefapiamwlgvigifygawmafaqtdikrliaytsvshmgfvliaiytgsqlayqgaviqmiahglsaaglfilcgqlyerihtrdmrmmgglwskmkwlpalslffavatlgmpgtgnfvgefmilfgsfqvvpvitvistfglvfasvyslamlhrayfgkaksqiasqelpgmslrelfmilllvvllvllgfypqpildtshsaigniqqwfvnsvtttrp Protein display]&nbsp;&nbsp;&nbsp; [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=nuoM+AND+escherichia+coli Pubmed(nuoM)]&nbsp;&nbsp;&nbsp; [http://trimer.tamu.edu/cgi-bin/textpresso/2.1/ecoli/search?searchstring=nuoM Textpresso(nuoM)]


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Revision as of 23:38, 21 January 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

nuoM

Gene Synonym(s)

ECK2271, b2277, JW2272[1]

Product Desc.

NuoM[2][3];

Component of NADH dehydrogenase I[2][3]

NADH:ubiquinone oxidoreductase subunit M, complex I; contains the ubiquinone-binding site, is homologus to antiporters, and is implicated in proton pumping[4]

Product Synonyms(s)

NADH:ubiquinone oxidoreductase, membrane subunit M[1], B2277[2][1], NuoM[2][1]

Function from GO

Cellular Component

Biological Process

Molecular Function

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): nuoABCEFGHIJKLMN[2], nuo1-14

Regulation/Activity
Quick Links

DNA display    Protein display    Pubmed(nuoM)    Textpresso(nuoM)

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See Help:Quickview for help with entering information in the Quickview table.

Notes

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NuoM and NuoL are located at the distal end of the membrane arm. the redox centers are in the peripheral arm.[4]



References

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  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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