nrdD:Quickview: Difference between revisions

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!align=left |Standard Name
!align=left {{table_heading_style}} |Standard Name
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''nrdD''  
''nrdD''  
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!align=left |Gene Synonym(s)
!align=left {{table_heading_style}} |Gene Synonym(s)
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''ECK4233, b4238, JW4197''<ref name='LIB:Riley_2006'/>
''ECK4233, b4238, JW4197''<ref name='LIB:Riley_2006'/>
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!align=left |Product Desc.
!align=left {{table_heading_style}} |Product Desc.
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ribonucleoside-triphosphate reductase<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;  
ribonucleoside-triphosphate reductase<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;  
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Ribonucleoside triphosphate reductase, class III, anaerobic<ref name='LIB:EcoGene'/>
Ribonucleoside triphosphate reductase, class III, anaerobic<ref name='LIB:EcoGene'/>
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!align=left |Product Synonyms(s)
!align=left {{table_heading_style}} |Product Synonyms(s)
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anaerobic ribonucleoside-triphosphate reductase<ref name='LIB:Riley_2006'/>, B4238<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, NrdD<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
anaerobic ribonucleoside-triphosphate reductase<ref name='LIB:Riley_2006'/>, B4238<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, NrdD<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
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!align=left |Knock-Out Phenotype
!align=left {{table_heading_style}} |Function from GO
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'''Molecular Function'''
* GO:0005515 protein binding ([http://www.geneontology.org/GO.evidence.shtml IPI])
* GO:0051065 CTP reductase activity ([http://www.geneontology.org/GO.evidence.shtml IDA])
* GO:0016961 class III ribonucleotide reductase activity ([http://www.geneontology.org/GO.evidence.shtml IMP])
'''Cellular Component'''
* GO:0031250 anaerobic ribonucleoside-triphosphate reductase complex ([http://www.geneontology.org/GO.evidence.shtml IMP])
'''Biological Process'''
* GO:0015949 nucleobase, nucleoside and nucleotide interconversion ([http://www.geneontology.org/GO.evidence.shtml IMP])


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!align=left |Regulation/Expression
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:nrdDG|nrdDG]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:nrdDG|nrdDG]]<ref name='LIB:EcoCyc10.6'/>  
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!align=left |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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!align=left {{table_heading_style}} |Quick Links
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[http://ecoliwiki.net/tools/display_dna.php?gene=nrdD&loc=MG1655:4460683..4458545,W3110:4467340..4465202,REL606:4445937..4443799,DH10B:4562491..4560353 DNA display]&nbsp;&nbsp;&nbsp; [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=4562491&end=4560353&gene=nrdD&aa=mtphvmkrdgckvpfkserikeailraakaaevddadycatvaavvseqmqgrnqvdineiqtavenqlmsgpykqlarayieyrhdrdierekrgrlnqeirglveqtnasllnenankdskviptqrdllagivakhyarqhllprdvvqahergdihyhdldyspffpmfncmlidlkgmltqgfkmgnaeieppksistatavtaqiiaqvashiyggttinridevlapfvtasynkhrktaeewnipdaegyansrtikecydafqsleyevntlhtangqtpfvtfgfglgtswesrliqesilrnriaglgknrktavfpklvfairdglnhkkgdpnydikqlalecaskrmypdilnydqvvkvtgsfktpmgcrsflgvwenengeqihdgrnnlgvislnlprialeakgdeatfwkllderlvlarkalmtriarlegvkarvapilymegacgvrlnadddvseifkngrasislgyigihetinalfggehvydneqlrakgiaiverlrqavdqwkeetgygfslystpsenlcdrfcrldtaefgvvpgvtdkgyytnsfhldvekkvnpydkidfeapypplanggficygeypniqhnlkaledvwdysyqhvpyygtntpidecyecgftgefectskgftcpkcgnhdasrvsvtrrvcgylgspdarpfnagkqeevkrrvkhlgngqig Protein display]&nbsp;&nbsp;&nbsp; [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=nrdD+AND+escherichia+coli Pubmed(nrdD)]&nbsp;&nbsp;&nbsp; [http://trimer.tamu.edu/cgi-bin/textpresso/2.1/ecoli/search?searchstring=nrdD Textpresso(nrdD)]


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Revision as of 23:39, 21 January 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

nrdD

Gene Synonym(s)

ECK4233, b4238, JW4197[1]

Product Desc.

ribonucleoside-triphosphate reductase[2][3];

Component of ribonucleoside-triphosphate reductase[2][3]; anaerobic nucleoside-triphosphate reductase activating system[2][3]

Ribonucleoside triphosphate reductase, class III, anaerobic[4]

Product Synonyms(s)

anaerobic ribonucleoside-triphosphate reductase[1], B4238[2][1], NrdD[2][1]

Function from GO

Molecular Function

Cellular Component

  • GO:0031250 anaerobic ribonucleoside-triphosphate reductase complex (IMP)

Biological Process

  • GO:0015949 nucleobase, nucleoside and nucleotide interconversion (IMP)
Knock-Out Phenotype
Regulation/Expression

transcription unit(s): nrdDG[2]

Regulation/Activity
Quick Links

DNA display    Protein display    Pubmed(nrdD)    Textpresso(nrdD)

edit table

See Help:Quickview for help with entering information in the Quickview table.

Notes

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Activated NrdD is predicted to be cleaved by oxygen at the Gly681 radical, dropping the last 31 aa. Requires AdoMet for oxidation of the iron-sulfur center and glycine radical formation. FNR regulon. Binds TrxA (Kumar, 2004).[4]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 3.2 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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