mfd:Quickview: Difference between revisions

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!align=left |Standard Name
!align=left {{table_heading_style}} |Standard Name
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''mfd''  
''mfd''  
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!align=left |Gene Synonym(s)
!align=left {{table_heading_style}} |Gene Synonym(s)
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''ECK1100, b1114, JW1100''<ref name='LIB:Riley_2006'/>
''ECK1100, b1114, JW1100''<ref name='LIB:Riley_2006'/>
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!align=left |Product Desc.
!align=left {{table_heading_style}} |Product Desc.
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transcription-repair coupling factor<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
transcription-repair coupling factor<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
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Transcription repair coupling factor<ref name='LIB:EcoGene'/>
Transcription repair coupling factor<ref name='LIB:EcoGene'/>
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!align=left |Product Synonyms(s)
!align=left {{table_heading_style}} |Product Synonyms(s)
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transcription-repair coupling factor<ref name='LIB:Riley_2006'/>, B1114<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Mfd<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, TRCF<ref name='LIB:EcoCyc11.1'/><ref name='LIB:Riley_2006'/>  
transcription-repair coupling factor<ref name='LIB:Riley_2006'/>, B1114<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Mfd<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, TRCF<ref name='LIB:EcoCyc11.1'/><ref name='LIB:Riley_2006'/>  
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!align=left |Knock-Out Phenotype
!align=left {{table_heading_style}} |Function from GO
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'''Molecular Function'''
* GO:0005515 protein binding ([http://www.geneontology.org/GO.evidence.shtml IPI])


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!align=left |Regulation/Expression
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:mfd|mfd]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:mfd|mfd]]<ref name='LIB:EcoCyc10.6'/>  
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!align=left |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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!align=left {{table_heading_style}} |Quick Links
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[http://ecoliwiki.net/tools/display_dna.php?gene=mfd&loc=MG1655:1173187..1169741,W3110:1175541..1172095,DH10B:1228632..1225186,REL606:1188559..1185113 DNA display]&nbsp;&nbsp;&nbsp; [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=1188559&end=1185113&gene=mfd&aa=mpeqyrytlpvkageqrllgeltgaacatlvaeiaerhagpvvliapdmqnalrlhdeisqftdqmvmnladwetlpydsfsphqdiissrlstlyqlptmqrgvlivpvntlmqrvcphsflhghalvmkkgqrlsrdalrtqldsagyrhvdqvmehgeyatrgalldlfpmgselpyrldffddeidslrvfdvdsqrtleeveainllpahefptdkaaielfrsqwrdtfevkrdpehiyqqvskgtlpagieywqplffseplpplfsyfpantllvntgdletsaerfqadtlarfenrgvdpmrpllppqslwlrvdelfselknwprvqlktehlptkaananlgfqklpdlavqaqqkapldalrkfletfdgpvvfsvesegrrealgellarikiapqrimrldeasdrgrylmigaaehgfvdtvrnlalicesdllgervarrrqdsrrtinpdtlirnlaelhigqpvvhlehgvgryagmttleaggitgeylmltyandaklyvpvsslhlisryaggaeenaplhklggdawsrarqkaaekvrdvaaelldiyaqraakegfafkhdreqyqlfcdsfpfettpdqaqainavlsdmcqplamdrlvcgdvgfgktevamraaflavdnhkqvavlvpttllaqqhydnfrdrfanwpvriemisrfrsakeqtqilaevaegkidiligthkllqsdvkfkdlgllivdeehrfgvrhkerikamranvdiltltatpiprtlnmamsgmrdlsiiatpparrlavktfvreydsmvvreailreilrggqvyylyndveniqkaaerlaelvpeariaighgqmrerelervmndfhhqrfnvlvcttiietgidiptantiiieradhfglaqlhqlrgrvgrshhqayawlltphpkamttdaqkrleaiasledlgagfalathdleirgagellgeeqsgsmetigfslymellenavdalkagrepsledltsqqtevelrmpsllpddfipdvntrlsfykriasakteneleeikvelidrfgllpdpartlldiarlrqqaqklgirklegnekggviefaeknhvnpawligllqkqpqhyrldgptrlkfiqdlserktriewvrqfmreleenaia Protein display]&nbsp;&nbsp;&nbsp; [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=mfd+AND+escherichia+coli Pubmed(mfd)]&nbsp;&nbsp;&nbsp; [http://trimer.tamu.edu/cgi-bin/textpresso/2.1/ecoli/search?searchstring=mfd Textpresso(mfd)]


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Revision as of 23:43, 21 January 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

mfd

Gene Synonym(s)

ECK1100, b1114, JW1100[1]

Product Desc.

transcription-repair coupling factor[2][3]

Transcription repair coupling factor[4]

Product Synonyms(s)

transcription-repair coupling factor[1], B1114[2][1], Mfd[2][1], TRCF[3][1]

Function from GO

Molecular Function

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): mfd[2]

Regulation/Activity
Quick Links

DNA display    Protein display    Pubmed(mfd)    Textpresso(mfd)

See Help:Quickview for help with entering information in the Quickview table.

Notes

[back to top]


Mfd dissociates transcription elongation complexes blocked at nonpairing lesions and mediates recruitment of DNA repair proteins. Arrested (backtracked) RNAP complexes are are also rescued by Mfd promoting forward translocation. Mfd structure resembles UvrB, including UvrA binding site, but no ATP-binding site.[4]



References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.