menD:Quickview: Difference between revisions

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!align=left |Standard Name
!align=left {{table_heading_style}} |Standard Name
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''menD''  
''menD''  
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!align=left |Gene Synonym(s)
!align=left {{table_heading_style}} |Gene Synonym(s)
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''ECK2258, b2264, JW5374''<ref name='LIB:Riley_2006'/>
''ECK2258, b2264, JW5374''<ref name='LIB:Riley_2006'/>
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!align=left |Product Desc.
!align=left {{table_heading_style}} |Product Desc.
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MEND<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;  
MEND<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;  
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SEPHCHC synthase, menaquinone biosynthesis<ref name='LIB:EcoGene'/>
SEPHCHC synthase, menaquinone biosynthesis<ref name='LIB:EcoGene'/>
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!align=left |Product Synonyms(s)
!align=left {{table_heading_style}} |Product Synonyms(s)
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bifunctional 2-oxoglutarate decarboxylase and SHCHC synthase<ref name='LIB:Riley_2006'/>, B2264<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, MenD<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
bifunctional 2-oxoglutarate decarboxylase and SHCHC synthase<ref name='LIB:Riley_2006'/>, B2264<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, MenD<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
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!align=left |Knock-Out Phenotype
!align=left {{table_heading_style}} |Function from GO
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'''Biological Process'''
* GO:0009234 menaquinone biosynthetic process ([http://www.geneontology.org/GO.evidence.shtml IMP])
'''Molecular Function'''
* GO:0046410 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase activity ([http://www.geneontology.org/GO.evidence.shtml IDA])
* GO:0070204 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase activity ([http://www.geneontology.org/GO.evidence.shtml IDA])


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!align=left |Regulation/Expression
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:menFD-yfbB-menBCE|menFD-yfbB-menBCE]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:menFD-yfbB-menBCE|menFD-yfbB-menBCE]]<ref name='LIB:EcoCyc10.6'/>  
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!align=left |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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!align=left {{table_heading_style}} |Quick Links
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[http://ecoliwiki.net/tools/display_dna.php?gene=menD&loc=MG1655:2377281..2375611,W3110:2383929..2382259,REL606:2325772..2324102,DH10B:2468269..2466599 DNA display]&nbsp;&nbsp;&nbsp; [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=2468269&end=2466599&gene=menD&aa=msvsafnrrwaavilealtrhgvrhiciapgsrstpltlaaaensafihhthfderglghlalglakvskqpvavivtsgtavanlypalieagltgeklilltadrppelidcganqairqpgmfashpthsislprptqdiparwlvstidhalgtlhaggvhincpfaeplygemddtglswqqrlgdwwqddkpwlreaprlesekqrdwffwrqkrgvvvagrmsaeegkkvalwaqtlgwpligdvlsqtgqplpcadlwlgnakatselqqaqivvqlgssltgkrllqwqascepeeywivddiegrldpahhrgrrlianiadwlelhpaekrqpwcveiprlaeqamqaviarrdafgeaqlahricdylpeqgqlfvgnslvvrlidalsqlpagypvysnrgasgidgllstaagvqrasgkptlaivgdlsalydlnalallrqvsaplvlivvnnnggqifsllptpqsererfylmpqnvhfehaaamfelkyhrpqnwqeletafadawrtptttviemvvndtdgaqtlqqllaqvshl Protein display]&nbsp;&nbsp;&nbsp; [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=menD+AND+escherichia+coli Pubmed(menD)]&nbsp;&nbsp;&nbsp; [http://trimer.tamu.edu/cgi-bin/textpresso/2.1/ecoli/search?searchstring=menD Textpresso(menD)]


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Revision as of 23:44, 21 January 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

menD

Gene Synonym(s)

ECK2258, b2264, JW5374[1]

Product Desc.

MEND[2][3];

Component of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase[3]

SEPHCHC synthase, menaquinone biosynthesis[4]

Product Synonyms(s)

bifunctional 2-oxoglutarate decarboxylase and SHCHC synthase[1], B2264[2][1], MenD[2][1]

Function from GO

Biological Process

Molecular Function

  • GO:0046410 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase activity (IDA)
  • GO:0070204 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase activity (IDA)
Knock-Out Phenotype
Regulation/Expression

transcription unit(s): menFD-yfbB-menBCE[2]

Regulation/Activity
Quick Links

DNA display    Protein display    Pubmed(menD)    Textpresso(menD)

edit table

See Help:Quickview for help with entering information in the Quickview table.

Notes

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Mistakenly thought to be SHCHC synthase (Jiang, 2007). SEPHCHC is 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic acid and SHCHC is 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate.[4]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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