iraP:Quickview: Difference between revisions

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!align=left |Standard Name
!align=left {{table_heading_style}} |Standard Name
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''iraP''  
''iraP''  
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!align=left |Gene Synonym(s)
!align=left {{table_heading_style}} |Gene Synonym(s)
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''yaiB, ECK0377, b0382, JW0373''<ref name='LIB:Riley_2006'/><ref name='LIB:EcoCyc10.6'/>
''yaiB, ECK0377, b0382, JW0373''<ref name='LIB:Riley_2006'/><ref name='LIB:EcoCyc10.6'/>
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!align=left |Product Desc.
!align=left {{table_heading_style}} |Product Desc.
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anti-adaptor protein for &sigma;<sup>S</sup> stabilization<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
anti-adaptor protein for &sigma;<sup>S</sup> stabilization<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
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RpoS stabilzer during Pi starvation, anti-RssB factor<ref name='LIB:EcoGene'/>
RpoS stabilzer during Pi starvation, anti-RssB factor<ref name='LIB:EcoGene'/>
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!align=left |Product Synonyms(s)
!align=left {{table_heading_style}} |Product Synonyms(s)
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predicted protein<ref name='LIB:Riley_2006'/>, B0382<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YaiB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, IraP<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
predicted protein<ref name='LIB:Riley_2006'/>, B0382<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YaiB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, IraP<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
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!align=left |Knock-Out Phenotype
!align=left {{table_heading_style}} |Function from GO
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'''Biological Process'''
* GO:0016036 cellular response to phosphate starvation ([http://www.geneontology.org/GO.evidence.shtml IMP,IEP])
* GO:0042177 negative regulation of protein catabolic process ([http://www.geneontology.org/GO.evidence.shtml IDA])
'''Molecular Function'''
* GO:0043856 anti-sigma factor antagonist activity ([http://www.geneontology.org/GO.evidence.shtml IDA])
* GO:0005515 protein binding ([http://www.geneontology.org/GO.evidence.shtml IPI])


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!align=left |Regulation/Expression
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:yaiB|yaiB]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:yaiB|yaiB]]<ref name='LIB:EcoCyc10.6'/>  
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!align=left |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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!align=left {{table_heading_style}} |Quick Links
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[http://ecoliwiki.net/tools/display_dna.php?gene=iraP&loc=MG1655:400610..400870,W3110:400610..400870,DH10B:339941..340201 DNA display]&nbsp;&nbsp;&nbsp; [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=339941&end=340201&gene=iraP&aa=mknliaellfklaqkeeeskelcaqvealeiivtamlrnmaqndqqrlidqvegalyevkpdasipdddtellrdyvkkllkhprq Protein display]&nbsp;&nbsp;&nbsp; [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=iraP+AND+escherichia+coli Pubmed(iraP)]&nbsp;&nbsp;&nbsp; [http://trimer.tamu.edu/cgi-bin/textpresso/2.1/ecoli/search?searchstring=iraP Textpresso(iraP)]


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Revision as of 23:48, 21 January 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

iraP

Gene Synonym(s)

yaiB, ECK0377, b0382, JW0373[1][2]

Product Desc.

anti-adaptor protein for σS stabilization[2][3]

RpoS stabilzer during Pi starvation, anti-RssB factor[4]

Product Synonyms(s)

predicted protein[1], B0382[2][1], YaiB[2][1], IraP[2][1]

Function from GO

Biological Process

Molecular Function

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): yaiB[2]

Regulation/Activity
Quick Links

DNA display    Protein display    Pubmed(iraP)    Textpresso(iraP)

See Help:Quickview for help with entering information in the Quickview table.

Notes

[back to top]


IraP interferes with RssB, ClpXP-dependent degradation of RpoS by interacting directly with RssB.[4]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.

[1] [2] [3]

  1. ↑ Bougdour, A et al. (2006) Modulating RssB activity: IraP, a novel regulator of sigma(S) stability in Escherichia coli. Genes Dev. 20 884-97 PubMed
  2. ↑ Tu, X et al. (2006) The PhoP/PhoQ two-component system stabilizes the alternative sigma factor RpoS in Salmonella enterica. Proc. Natl. Acad. Sci. U.S.A. 103 13503-8 PubMed
  3. ↑ Bougdour, A & Gottesman, S (2007) ppGpp regulation of RpoS degradation via anti-adaptor protein IraP. Proc. Natl. Acad. Sci. U.S.A. 104 12896-901 PubMed