glnD:Quickview: Difference between revisions
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!align=left | !align=left {{table_heading_style}} |Standard Name | ||
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''glnD'' | ''glnD'' | ||
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!align=left | !align=left {{table_heading_style}} |Gene Synonym(s) | ||
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''ECK0165, b0167, JW0162, glnD5''<ref name='LIB:Riley_2006'/> | ''ECK0165, b0167, JW0162, glnD5''<ref name='LIB:Riley_2006'/> | ||
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!align=left | !align=left {{table_heading_style}} |Product Desc. | ||
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GLND<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/> | GLND<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/> | ||
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Bifunctional uridylyltransferase/uridylyl-removing enzyme; (UTase/UR); controls uridylylation state and activity of PII(GlnB)<ref name='LIB:EcoGene'/> | Bifunctional uridylyltransferase/uridylyl-removing enzyme; (UTase/UR); controls uridylylation state and activity of PII(GlnB)<ref name='LIB:EcoGene'/> | ||
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!align=left | !align=left {{table_heading_style}} |Product Synonyms(s) | ||
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uridylyltransferase<ref name='LIB:Riley_2006'/>, B0167<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, GlnD<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> | uridylyltransferase<ref name='LIB:Riley_2006'/>, B0167<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, GlnD<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> | ||
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!align=left | !align=left {{table_heading_style}} |Function from GO | ||
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!align=left | !align=left {{table_heading_style}} |Knock-Out Phenotype | ||
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!align=left {{table_heading_style}} |Regulation/Expression | |||
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transcription unit(s): [[:Category:Txn_unit:dapD|dapD]]<ref name='LIB:EcoCyc10.6'/> | transcription unit(s): [[:Category:Txn_unit:dapD|dapD]]<ref name='LIB:EcoCyc10.6'/> | ||
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!align=left | !align=left {{table_heading_style}} |Regulation/Activity | ||
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!align=left {{table_heading_style}} |Quick Links | |||
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[http://ecoliwiki.net/tools/display_dna.php?gene=glnD&loc=MG1655:188650..185978,W3110:188650..185978,DH10B:162754..160082,REL606:191492..188820 DNA display] [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=191492&end=188820&gene=glnD&aa=mntlpeqyantalptlpgqpqnpcvwprdeltvggikahidtfqrwlgdafdngisaeqlieartefidqllqrlwieagfsqiadlalvavggygrgelhplsdvdllilsrkklpddqaqkvgelltllwdvklevghsvrtleecmleglsdltvatnliesrlligdvalflelqkhifsegfwpsdkfyaakveeqnqrhqryhgtsynlepdiksspgglrdihtlqwvarrhfgatsldemvgfgfltsaeraelneclhilwrirfalhlvvsrydnrllfdrqlsvaqrlnysgegnepvermmkdyfrvtrrvselnqmllqlfdeailalpadekprpiddefqlrgtlidlrdetlfmrqpeailrmfytmvhnsaitgiysttlrqlrharrhlqqplcnipearklflsilrhpgavrrgllpmhrhsvlgaympqwshivgqmqfdlfhaytvdehtirvmlklesfaseetrqrhplcvdvwprlpstelifiaalfhdiakgrggdhsilgaqdvvhfaelhglnsretqlvawlvrqhllmsvtaqrrdiqdpevikqfaeevqtenrlrylvcltvadicatnetlwnswkqsllrelyfatekqlrrgmqntpdmrervrhhqlqalallrmdnideealhqiwsrcranyfvrhspnqlawharhllqhdlskplvllspqatrggteifiwspdrpylfaavcaeldrrnlsvhdaqifttrdgmamdtfivlepdgnplsadrhevirfgleqvltqsswqppqprrqpaklrhftvetevtflpthtdrksflelialdqpgllarvgkifadlgislhgarittigervedlfiiatadrralnnelqqevhqrltealnpndkg Protein display] [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=glnD+AND+escherichia+coli Pubmed(glnD)] [http://trimer.tamu.edu/cgi-bin/textpresso/2.1/ecoli/search?searchstring=glnD Textpresso(glnD)] | |||
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Revision as of 23:55, 21 January 2010
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
See Help:Quickview for help with entering information in the Quickview table.
| Standard Name |
glnD |
|---|---|
| Gene Synonym(s) |
ECK0165, b0167, JW0162, glnD5[1] |
| Product Desc. |
Bifunctional uridylyltransferase/uridylyl-removing enzyme; (UTase/UR); controls uridylylation state and activity of PII(GlnB)[4] |
| Product Synonyms(s) | |
| Function from GO | |
| Knock-Out Phenotype | |
| Regulation/Expression | |
| Regulation/Activity | |
| Quick Links | |
| edit table |
See Help:Quickview for help with entering information in the Quickview table.
Notes
GlnD has both a uridylyltransferase and a uridylyl-removing activity. The only known substrates for GlnD are the two PII proteins GlnB and GlnK. In both cases GlnD covalently modifies residue Tyr51 in the T-loop of the substrate thereby controlling the ability of GlnB and GlnK to interact with their specific targets. The activity of GlnD is controlled by the intracellular glutamine availability. Glutamine inhibits the transferase action of GlnD and as a consequence GlnB and GlnK are deuridylylated in N-sufficient conditions. [Comment provided by EcoTeam member Mike Merrick, 11.16.06][4]
References
- ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.