dctR:Quickview: Difference between revisions

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!align=left |Standard Name
!align=left {{table_heading_style}} |Standard Name
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''dctR''  
''dctR''  
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!align=left |Gene Synonym(s)
!align=left {{table_heading_style}} |Gene Synonym(s)
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''yhiF, ECK3491, b3507, JW3475''<ref name='LIB:Riley_2006'/><ref name='LIB:EcoCyc10.6'/>
''yhiF, ECK3491, b3507, JW3475''<ref name='LIB:Riley_2006'/><ref name='LIB:EcoCyc10.6'/>
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!align=left |Product Desc.
!align=left {{table_heading_style}} |Product Desc.
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protein involved in metabolism of C4-dicarboxylates<ref name='LIB:EcoCyc10.6'/>; predicted DNA-binding transcriptional regulator<ref name='LIB:EcoCyc11.1'/>
protein involved in metabolism of C4-dicarboxylates<ref name='LIB:EcoCyc10.6'/>; predicted DNA-binding transcriptional regulator<ref name='LIB:EcoCyc11.1'/>
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Probable repressor of dctA dicarboxylate transporter gene<ref name='LIB:EcoGene'/>
Probable repressor of dctA dicarboxylate transporter gene<ref name='LIB:EcoGene'/>
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!align=left |Product Synonyms(s)
!align=left {{table_heading_style}} |Product Synonyms(s)
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predicted DNA-binding ranscriptional regulator<ref name='LIB:Riley_2006'/>, B3507<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, DctR<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YhiF<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
predicted DNA-binding ranscriptional regulator<ref name='LIB:Riley_2006'/>, B3507<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, DctR<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YhiF<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
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!align=left |Knock-Out Phenotype
!align=left {{table_heading_style}} |Function from GO
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'''Biological Process'''
* GO:0001101 response to acid ([http://www.geneontology.org/GO.evidence.shtml IMP])
* GO:0043471 regulation of cellular carbohydrate catabolic process ([http://www.geneontology.org/GO.evidence.shtml IGI])
'''Molecular Function'''
* GO:0030528 transcription regulator activity ([http://www.geneontology.org/GO.evidence.shtml ISS,HINF])


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!align=left |Regulation/Expression
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:yhiF|yhiF]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:yhiF|yhiF]]<ref name='LIB:EcoCyc10.6'/>  
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!align=left |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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!align=left {{table_heading_style}} |Quick Links
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[http://ecoliwiki.net/tools/display_dna.php?gene=dctR&loc=MG1655:3652706..3653236,W3110:3985732..3985202 DNA display]&nbsp;&nbsp;&nbsp; [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=3985732&end=3985202&gene=dctR&aa=mfliitrdtmfftamknilskgnvvhiqneeeidvmlhqnafviidtlmnnvfhsnfltqierlkpvhviifspfnikrclgkvpvtfvprtitiidfvalingsycsvpeaavslsrkqhqvlscianqmttedileklkislktfychkhnimmilnlkrinelvrhqhidylv Protein display]&nbsp;&nbsp;&nbsp; [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=dctR+AND+escherichia+coli Pubmed(dctR)]&nbsp;&nbsp;&nbsp; [http://trimer.tamu.edu/cgi-bin/textpresso/2.1/ecoli/search?searchstring=dctR Textpresso(dctR)]


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Revision as of 00:04, 22 January 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

dctR

Gene Synonym(s)

yhiF, ECK3491, b3507, JW3475[1][2]

Product Desc.

protein involved in metabolism of C4-dicarboxylates[2]; predicted DNA-binding transcriptional regulator[3]

Probable repressor of dctA dicarboxylate transporter gene[4]

Product Synonyms(s)

predicted DNA-binding ranscriptional regulator[1], B3507[2][1], DctR[2][1], YhiF[2][1]

Function from GO

Biological Process

Molecular Function

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): yhiF[2]

Regulation/Activity
Quick Links

DNA display    Protein display    Pubmed(dctR)    Textpresso(dctR)

See Help:Quickview for help with entering information in the Quickview table.

Notes

[back to top]


DctR is in the EvgAS regulon. Mutation reverses succinate growth defect of an atp operon deletion, as does a DctA overproducer. Overproduced DctR blocks growth on succinate, presumably by repressing dctA. Overexpression of DctR causes filamentous biofilm formation. DctR is a member of the LuxR family of regulatory proteins and is homologous to the DctR response regulator of R. capsulatus. DctR is possibly involved in the regulation of type III secretion systems in enterohemorrhagic E. coli O157:H7.[4]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.