cheY:Quickview: Difference between revisions

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!align=left |Standard Name
!align=left {{table_heading_style}} |Standard Name
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''cheY''  
''cheY''  
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!align=left |Gene Synonym(s)
!align=left {{table_heading_style}} |Gene Synonym(s)
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''ECK1883, b1882, JW1871''<ref name='LIB:Riley_2006'/>
''ECK1883, b1882, JW1871''<ref name='LIB:Riley_2006'/>
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!align=left |Product Desc.
!align=left {{table_heading_style}} |Product Desc.
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chemotaxis regulator transmitting signal to flagellar motor component<ref name='LIB:Riley_2006'/>
chemotaxis regulator transmitting signal to flagellar motor component<ref name='LIB:Riley_2006'/>
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Response regulator for chemotactic signal transduction; CheA is the cognate sensor protein<ref name='LIB:EcoGene'/>
Response regulator for chemotactic signal transduction; CheA is the cognate sensor protein<ref name='LIB:EcoGene'/>
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!align=left |Product Synonyms(s)
!align=left {{table_heading_style}} |Product Synonyms(s)
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B1882<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>
B1882<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>
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!align=left |Knock-Out Phenotype
!align=left {{table_heading_style}} |Function from GO
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'''Biological Process'''
* GO:0006473 protein amino acid acetylation ([http://www.geneontology.org/GO.evidence.shtml IDA])


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!align=left |Regulation/Expression
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:tar-tap-cheRBYZ|tar-tap-cheRBYZ]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:tar-tap-cheRBYZ|tar-tap-cheRBYZ]]<ref name='LIB:EcoCyc10.6'/>  
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!align=left |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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!align=left {{table_heading_style}} |Quick Links
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[http://ecoliwiki.net/tools/display_dna.php?gene=cheY&loc=MG1655:1965461..1965072,W3110:1969151..1968762,DH10B:2056032..2055643,REL606:1946207..1945818 DNA display]&nbsp;&nbsp;&nbsp; [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=1946207&end=1945818&gene=cheY&aa=madkelkflvvddfstmrrivrnllkelgfnnveeaedgvdalnklqaggygfvisdwnmpnmdglellktiradgamsalpvlmvtaeakkeniiaaaqagasgyvvkpftaatleeklnkifeklgm Protein display]&nbsp;&nbsp;&nbsp; [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=cheY+AND+escherichia+coli Pubmed(cheY)]&nbsp;&nbsp;&nbsp; [http://trimer.tamu.edu/cgi-bin/textpresso/2.1/ecoli/search?searchstring=cheY Textpresso(cheY)]


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Revision as of 00:07, 22 January 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

cheY

Gene Synonym(s)

ECK1883, b1882, JW1871[1]

Product Desc.

chemotaxis regulator transmitting signal to flagellar motor component[1]

Response regulator for chemotactic signal transduction; CheA is the cognate sensor protein[2]

Product Synonyms(s)

B1882[3][1]

Function from GO

Biological Process

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): tar-tap-cheRBYZ[3]

Regulation/Activity
Quick Links

DNA display    Protein display    Pubmed(cheY)    Textpresso(cheY)

See Help:Quickview for help with entering information in the Quickview table.

Notes

[back to top]


CheY is acetylated at lysine residues 92 and 109 by acetyl-CoA synthase (Acs). Proposed mechanism for optimum chemotaxis suggests alteration of side chain signaling state by rotation of Tyr106 side chain; this is presumably modulated by phosphorylation state of the molecule. A mutation resulting in a tyrosine to tryptophan substitution at position 106 results in a hyperactive phenotype, while a double mutation T87I/Y106W resulted in loss of activity. Substitutions at ILE95 affect FliM binding. Flagellar regulon.[2]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  3. ↑ 3.0 3.1 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7