acrE:Quickview: Difference between revisions

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!align=left |Standard Name
!align=left {{table_heading_style}} |Standard Name
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''acrE''  
''acrE''  
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!align=left |Gene Synonym(s)
!align=left {{table_heading_style}} |Gene Synonym(s)
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''ECK3252, b3265, JW3233, G7979''<ref name='LIB:Riley_2006'/><ref name='LIB:EcoCyc10.6'/>
''ECK3252, b3265, JW3233, G7979''<ref name='LIB:Riley_2006'/><ref name='LIB:EcoCyc10.6'/>
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!align=left |Product Desc.
!align=left {{table_heading_style}} |Product Desc.
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transmembrane protein affects septum formation and cell membrane permeability<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;  
transmembrane protein affects septum formation and cell membrane permeability<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;  
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AcrEF-TolC efflux pump, multidrug/solvent resistance; membrane-fusion lipoprotein<ref name='LIB:EcoGene'/>
AcrEF-TolC efflux pump, multidrug/solvent resistance; membrane-fusion lipoprotein<ref name='LIB:EcoGene'/>
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!align=left |Product Synonyms(s)
!align=left {{table_heading_style}} |Product Synonyms(s)
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cytoplasmic membrane lipoprotein<ref name='LIB:Riley_2006'/>, B3265<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, AcrE<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
cytoplasmic membrane lipoprotein<ref name='LIB:Riley_2006'/>, B3265<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, AcrE<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
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!align=left |Knock-Out Phenotype
!align=left {{table_heading_style}} |Function from GO
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'''Biological Process'''
* GO:0042493 response to drug ([http://www.geneontology.org/GO.evidence.shtml ISS])
'''Cellular Component'''
* GO:0031226 intrinsic to plasma membrane ([http://www.geneontology.org/GO.evidence.shtml IMP])


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!align=left |Regulation/Expression
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:acrEF|acrEF]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:acrEF|acrEF]]<ref name='LIB:EcoCyc10.6'/>  
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!align=left |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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!align=left {{table_heading_style}} |Quick Links
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[http://ecoliwiki.net/tools/display_dna.php?gene=acrE&loc=MG1655:3411886..3413043,W3110:3413719..3414876,REL606:3341755..3342912,DH10B:3509631..3510788 DNA display]&nbsp;&nbsp;&nbsp; [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=3509631&end=3510788&gene=acrE&aa=mtkharffllpsfilisaaliagcndkgeekahvgepqvtvhivktaplevktelpgrtnayriaevrpqvsgivlnrnftegsdvqagqslyqidpatyqanydsakgelakseaaaaiahltvkryvplvgtkyisqqeydqaiadarqadaaviaakatvesarinlaytkvtapisgrigkstvtegalvtngqttelatvqqldpiyvdvtqssndfmrlkqsveqgnlhkenatsnvelvmengqtyplkgtlqfsdvtvdestgsitlravfpnpqhtllpgmfvraridegvqpdailipqqgvsrtprgdatvlivndksqvearpvvasqaigdkwliseglksgdqvivsglqkarpgeqvkattdtpadtask Protein display]&nbsp;&nbsp;&nbsp; [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=acrE+AND+escherichia+coli Pubmed(acrE)]&nbsp;&nbsp;&nbsp; [http://trimer.tamu.edu/cgi-bin/textpresso/2.1/ecoli/search?searchstring=acrE Textpresso(acrE)]


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Revision as of 00:13, 22 January 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

acrE

Gene Synonym(s)

ECK3252, b3265, JW3233, G7979[1][2]

Product Desc.

transmembrane protein affects septum formation and cell membrane permeability[2][3];

Component of AcrEF-TolC Multidrug Efflux Transport System[3]

AcrEF-TolC efflux pump, multidrug/solvent resistance; membrane-fusion lipoprotein[4]

Product Synonyms(s)

cytoplasmic membrane lipoprotein[1], B3265[2][1], AcrE[2][1]

Function from GO

Biological Process

Cellular Component

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): acrEF[2]

Regulation/Activity
Quick Links

DNA display    Protein display    Pubmed(acrE)    Textpresso(acrE)

edit table

See Help:Quickview for help with entering information in the Quickview table.

Notes

[back to top]


AcrE is attached to the inner membrane. AcrEF confers resistance to nalidixic acid, acriflavin, indole and solvents. acrE is an acrA paralog. May have role in cell division. First 23 aa are a type II signal peptide.[4]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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