thiM:Quickview: Difference between revisions

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!align=left {{table_heading_style}} |Standard Name
!align=left |Standard Name
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''thiM''  
''thiM''  
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!align=left {{table_heading_style}} |Gene Synonym(s)
!align=left |Gene Synonym(s)
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''ECK2097, b2104, JW2091''<ref name='LIB:Riley_2006'/>
''ECK2097, b2104, JW2091''<ref name='LIB:Riley_2006'/>
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!align=left {{table_heading_style}} |Product Desc.
!align=left |Product Desc.
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hydroxyethylthiazole kinase<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
hydroxyethylthiazole kinase<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
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Hydroxyethylthiazole kinase<ref name='LIB:EcoGene'/>
Hydroxyethylthiazole kinase<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Product Synonyms(s)
!align=left |Product Synonyms(s)
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hydoxyethylthiazole kinase<ref name='LIB:Riley_2006'/>, B2104<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, ThiM<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, 4-methyl-5-(&beta;-hydroxyethyl)thiazole kinase<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, ATP:4-methyl-5-(2-hydroxyethyl)-thiazole 2-phosphotransferase<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, THZ kinase<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
hydoxyethylthiazole kinase<ref name='LIB:Riley_2006'/>, B2104<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, ThiM<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, 4-methyl-5-(&beta;-hydroxyethyl)thiazole kinase<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, ATP:4-methyl-5-(2-hydroxyethyl)-thiazole 2-phosphotransferase<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, THZ kinase<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
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!align=left {{table_heading_style}} |Knock-Out Phenotype
!align=left |Knock-Out Phenotype
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!align=left {{table_heading_style}} |Regulation/Expression
!align=left |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:thiD|thiD]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:thiD|thiD]]<ref name='LIB:EcoCyc10.6'/>  
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!align=left {{table_heading_style}} |Regulation/Activity
!align=left |Regulation/Activity
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Revision as of 00:55, 10 January 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

thiM

Gene Synonym(s)

ECK2097, b2104, JW2091[1]

Product Desc.

hydroxyethylthiazole kinase[2][3]

Hydroxyethylthiazole kinase[4]

Product Synonyms(s)

hydoxyethylthiazole kinase[1], B2104[2][1], ThiM[2][1], 4-methyl-5-(β-hydroxyethyl)thiazole kinase[2][1], ATP:4-methyl-5-(2-hydroxyethyl)-thiazole 2-phosphotransferase[2][1], THZ kinase[2][1]

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): thiD[2]

Regulation/Activity


edit table

See Help:Quickview for help with entering information in the Quickview table.

Notes

[back to top]


thiMD operon expression is controlled by a thiamine pyrophosphate (TPP) responsive riboswitch in the 5' UTR. The thiM riboswitch is the target for the antibiotic pyrithiamine. The PDB links are to the structures of various thiM riboswitch/small molecule complexes: 2GDI, TPP; 2HOJ, TPP/Mn2+; 2HOK, TPP/Ca2+; 2HOL, TPP/Ba2+; 2HOM,TMP; 2HOO, BTP; 2HOP, PT (Serganov, 2006; Edwards, 2006).[4]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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