frmB:Quickview: Difference between revisions
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!align=left {{table_heading_style}} |Standard Name | !align=left {{table_heading_style}} |Standard Name | ||
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''frmB'' | |||
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!align=left {{table_heading_style}} |Gene Synonym(s) | !align=left {{table_heading_style}} |Gene Synonym(s) | ||
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''ECK0352, b0355, JW0346, yaiM''<ref name='LIB:Riley_2006'/> | |||
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!align=left {{table_heading_style}} |Product Desc. | !align=left {{table_heading_style}} |Product Desc. | ||
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<i>S</i>-formylglutathione hydrolase<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/> | |||
S-formylglutathione hydrolase, formaldehyde degradation<ref name='LIB:EcoGene'/> | |||
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!align=left {{table_heading_style}} |Product Synonyms(s) | !align=left {{table_heading_style}} |Product Synonyms(s) | ||
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predicted esterase<ref name='LIB:Riley_2006'/>, B0355<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YaiM<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, FrmB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> | |||
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!align=left {{table_heading_style}} |Knock-Out Phenotype | !align=left {{table_heading_style}} |Knock-Out Phenotype | ||
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!align=left {{table_heading_style}} |Regulation/Expression | !align=left {{table_heading_style}} |Regulation/Expression | ||
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transcription unit(s): [[:Category:Txn_unit:frmB|frmB]]<ref name='LIB:EcoCyc10.6'/> | |||
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!align=left {{table_heading_style}} |Regulation/Activity | !align=left {{table_heading_style}} |Regulation/Activity | ||
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Revision as of 20:36, 4 March 2009
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
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| Standard Name |
frmB |
|---|---|
| Gene Synonym(s) |
ECK0352, b0355, JW0346, yaiM[1] |
| Product Desc. |
S-formylglutathione hydrolase[2][3] S-formylglutathione hydrolase, formaldehyde degradation[4] |
| Product Synonyms(s) | |
| Knock-Out Phenotype | |
| Regulation/Expression | |
| Regulation/Activity |
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Notes
FrmB also has p-nitrophenyl C2-C6 fatty acid ester and a-naphthyl acetate carboxylesterase activities in vitro. The frmRAB operon is negatively regulated by frmR, is induced by formaldehyde, and probably degrades formaldehyde. FrmB is 50% identical to P. denitrificans S-formylglutathione hydrolase. FrmB and YeiG are 50% identical paralogs; double mutant is formaldehyde sensitive; this may explain why an frmB single mutant did not have a formadehyde phenotype when tested on Biolog plates (Herring, 2004). The amino terminal half of FrmB is homologus to the C-terminal half of YieL. S9 peptidase family; YeiG or FrmB are not in MEROPS yet, but it has homologs.[4]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.