clpS:Quickview: Difference between revisions

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!align=left {{table_heading_style}} |Standard Name
!align=left |Standard Name
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''clpS''  
''clpS''  
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!align=left {{table_heading_style}} |Gene Synonym(s)
!align=left |Gene Synonym(s)
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''ECK0872, b0881, JW0865, yljA''<ref name='LIB:Riley_2006'/>
''ECK0872, b0881, JW0865, yljA''<ref name='LIB:Riley_2006'/>
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!align=left {{table_heading_style}} |Product Desc.
!align=left |Product Desc.
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specificity factor for ClpA-ClpP chaperone-protease complex<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
specificity factor for ClpA-ClpP chaperone-protease complex<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
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Substrate modulator for ClpAP; directs protease activity towards aggregated proteins<ref name='LIB:EcoGene'/>
Substrate modulator for ClpAP; directs protease activity towards aggregated proteins<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Product Synonyms(s)
!align=left |Product Synonyms(s)
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regulatory protein for ClpA substrate specificity<ref name='LIB:Riley_2006'/>, ClpS<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YljA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, B0881<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
regulatory protein for ClpA substrate specificity<ref name='LIB:Riley_2006'/>, ClpS<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YljA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, B0881<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
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!align=left {{table_heading_style}} |Knock-Out Phenotype
!align=left |Knock-Out Phenotype
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!align=left {{table_heading_style}} |Regulation/Expression
!align=left |Regulation/Expression
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transcription unit(s):   
transcription unit(s):   
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!align=left {{table_heading_style}} |Regulation/Activity
!align=left |Regulation/Activity
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Revision as of 00:22, 9 January 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

clpS

Gene Synonym(s)

ECK0872, b0881, JW0865, yljA[1]

Product Desc.

specificity factor for ClpA-ClpP chaperone-protease complex[2][3]

Substrate modulator for ClpAP; directs protease activity towards aggregated proteins[4]

Product Synonyms(s)

regulatory protein for ClpA substrate specificity[1], ClpS[2][1], YljA[2][1], B0881[2][1]

Knock-Out Phenotype
Regulation/Expression

transcription unit(s):

Regulation/Activity


edit table

See Help:Quickview for help with entering information in the Quickview table.

Notes

[back to top]


ClpS is involved in degradation of N-end rule substrates by the ClpAP protease[5][6]

ClpS is needed for the degradation of N-end rule substrates by ClpAP. clpS is a non-essential gene. ClpS is homologous to eukaryotic E3 ubiquitin ligase n-recognin (Lupas, 2003).[4]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ Erbse, A et al. (2006) ClpS is an essential component of the N-end rule pathway in Escherichia coli. Nature 439 753-6 PubMed
  6. ↑ Wang, KH et al. (2007) ClpS modulates but is not essential for bacterial N-end rule degradation. Genes Dev. 21 403-8 PubMed
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