yjjG:Quickview: Difference between revisions

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[http://porteco.org/AjaxSearch.jsp?searchString=yjjG&s=search PortEco search(yjjG)]    [http://ecoliwiki.net/tools/display_dna.php?gene=yjjG&loc=MG1655:4606669..4607346,W3110:4613326..4614003,DH10B:4653131..4653808,REL606:4597880..4598557,BW2952:4545153..4545830 DNA display]    [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=4545153&end=4545830&gene=yjjG&aa=mkwdwiffdadetlftfdsftglqrmfldysvtftaedfqdyqavnkplwvdyqngaitslqlqhgrfeswaerlnvepgklneafinamaeictplpgavsllnairgnakigiitngfsalqqvrlertglrdyfdllviseevgvakpnkkifdyaleqagnpdrsrvlmvgdtaesdilgginaglatcwlnahhreqpegiaptwtvsslheleqllckh Protein display]    [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=yjjG+AND+escherichia+coli Pubmed(yjjG)]    [http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=yjjG Textpresso(yjjG)]
[http://porteco.org/AjaxSearch.jsp?searchString=yjjG&s=search PortEco search(yjjG)]    [http://ecoliwiki.net/tools/display_dna.php?gene=yjjG&loc=MG1655:4606669..4607346,W3110:4613326..4614003,DH10B:4653131..4653808,REL606:4597880..4598557,BW2952:4545153..4545830 DNA display]    [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=4545153&end=4545830&gene=yjjG&aa= Protein display]    [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=yjjG+AND+escherichia+coli Pubmed(yjjG)]    [http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=yjjG Textpresso(yjjG)]


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Revision as of 21:11, 16 August 2011

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

yjjG

Gene Synonym(s)

ECK4365, b4374, JW4336[1]

Product Desc.

pyrimidine nucleotidase[2][3]

Noncanonical pyrimidine nucleotide house-cleaning phosphatase; dUMP phosphatase activity[4]

Product Synonyms(s)

predicted hydrolase [1], B4374 [2][1], YjjG [2][1]

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): holD[2]

Regulation/Activity
Quick Links

PortEco search(yjjG)    DNA display    Protein display    Pubmed(yjjG)    Textpresso(yjjG)

See Help:Quickview for help with entering information in the Quickview table.

Notes

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Efficient in vitro substrates include: dUMP, UMP, and dTMP; phosphoramidase: in vitro activities demonstrated by Kuznetsova et al. (2005, 2006). yjjG mutants are sensitive to 5-fluoropyrimidine derivatives, such as 5-fluoro-2'-deoxyuridine (Titz, 2007). YjjG has a strict metal requirement for catalytic activity. Poorly utilized substrates include UDP, TDP and a variety of nucleotide monophosphates. A yjjG mutation blocks the utilization of thymine to feed a thyA auxotroph since it must first be converted to thymidine and dUMP dephosphorylated by YjjG is needed for that conversion (Weiss, 2006). YjjG is also called nucleoside 5'-monophosphate phosphohydrolase. HAD superfamily.[4]



References

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  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.