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!align=left {{table_heading_style}} |Function from GO
!align=left {{table_heading_style}} |Function from GO
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'''Biological Process'''
<GO_nr />
* GO:0002100 tRNA wobble adenosine to inosine editing ([http://www.geneontology.org/GO.evidence.shtml IDA])
'''Molecular Function'''
* GO:0008251 tRNA-specific adenosine deaminase activity ([http://www.geneontology.org/GO.evidence.shtml IDA])
 
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!align=left {{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Knock-Out Phenotype

Revision as of 19:27, 2 February 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

tadA

Gene Synonym(s)

ECK2557, b2559, JW2543, yfhC[1]

Product Desc.

TadA; of tRNA specific adenosine deaminase[2][3];

Component of tRNA-specific adenosine deaminase[3]

A34-tRNA adenosine deaminase; point mutation confers resistance to HokC(Gef)-mediated cell killing; essential gene; homodimeric[4]

Product Synonyms(s)

tRNA-specific adenosine deaminase[1], TadA[2][1], YfhC[2][1], B2559[2][1]

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): tadA[2]

Regulation/Activity
Quick Links

DNA display    Protein display    Pubmed(tadA)    Textpresso(tadA)

See Help:Quickview for help with entering information in the Quickview table.

Notes

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Previously reported non-essential nature was mistakenly based on an insertion that removed the last 17 aa, but the truncated enzyme is active. Three possible start sites annotated in various orthologs: -11, +1, and +12; alignment results ambiguous; +1 chosen due to best RBS.[4]



References

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  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.