yhdJ:Quickview: Difference between revisions

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!align=left |Standard Name
!align=left {{table_heading_style}} |Standard Name
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''yhdJ''  
''yhdJ''  
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!align=left |Gene Synonym(s)
!align=left {{table_heading_style}} |Gene Synonym(s)
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''ECK3249, b3262, JW5543, ccrM''<ref name='LIB:Riley_2006'/>
''ECK3249, b3262, JW5543, ccrM''<ref name='LIB:Riley_2006'/>
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!align=left |Product Desc.
!align=left {{table_heading_style}} |Product Desc.
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predicted methyltransferase<ref name='LIB:EcoCyc10.6'/>; DNA adenine methyltransferase<ref name='LIB:EcoCyc11.1'/>
predicted methyltransferase<ref name='LIB:EcoCyc10.6'/>; DNA adenine methyltransferase<ref name='LIB:EcoCyc11.1'/>
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DNA adenine methyltransferase, SAM-dependent<ref name='LIB:EcoGene'/>
DNA adenine methyltransferase, SAM-dependent<ref name='LIB:EcoGene'/>
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!align=left |Product Synonyms(s)
!align=left {{table_heading_style}} |Product Synonyms(s)
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predicted methyltransferase<ref name='LIB:Riley_2006'/>, B3262<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YhdJ<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, CcrM<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
predicted methyltransferase<ref name='LIB:Riley_2006'/>, B3262<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YhdJ<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, CcrM<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
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!align=left |Knock-Out Phenotype
!align=left {{table_heading_style}} |Function from GO
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'''Molecular Function'''
* GO:0009007 site-specific DNA-methyltransferase (adenine-specific) activity ([http://www.geneontology.org/GO.evidence.shtml IDA])


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!align=left |Regulation/Expression
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:yhdJ|yhdJ]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:yhdJ|yhdJ]]<ref name='LIB:EcoCyc10.6'/>  
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!align=left |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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!align=left {{table_heading_style}} |Quick Links
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[http://ecoliwiki.net/tools/display_dna.php?gene=yhdJ&loc=MG1655:3409675..3410559,W3110:3411508..3412392,REL606:3339544..3340428,DH10B:3507420..3508304 DNA display]&nbsp;&nbsp;&nbsp; [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=3507420&end=3508304&gene=yhdJ&aa=mtmrtgceptrfgneaktiihgdalaelkkipaesvdlifadppynigknfdglieawkedlfidwlfeviaechrvlkkqgsmyimnstenmpfidlqcrklftiksrivwsydssgvqakkhygsmyepilmmvkdaknytfngdailveaktgsqralidyrknppqpynhqkvpgnvwdfprvrylmdeyenhptqkpeallkriilassnpgdivldpfagsfttgavaiasgrkfigieinseyikmglrrldvashysaeelakvkkrktgnlskrsrlsevdpdlitk Protein display]&nbsp;&nbsp;&nbsp; [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=yhdJ+AND+escherichia+coli Pubmed(yhdJ)]&nbsp;&nbsp;&nbsp; [http://trimer.tamu.edu/cgi-bin/textpresso/2.1/ecoli/search?searchstring=yhdJ Textpresso(yhdJ)]


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Revision as of 23:00, 21 January 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

yhdJ

Gene Synonym(s)

ECK3249, b3262, JW5543, ccrM[1]

Product Desc.

predicted methyltransferase[2]; DNA adenine methyltransferase[3]

DNA adenine methyltransferase, SAM-dependent[4]

Product Synonyms(s)

predicted methyltransferase[1], B3262[2][1], YhdJ[2][1], CcrM[2][1]

Function from GO

Molecular Function

  • GO:0009007 site-specific DNA-methyltransferase (adenine-specific) activity (IDA)
Knock-Out Phenotype
Regulation/Expression

transcription unit(s): yhdJ[2]

Regulation/Activity
Quick Links

DNA display    Protein display    Pubmed(yhdJ)    Textpresso(yhdJ)

See Help:Quickview for help with entering information in the Quickview table.

Notes

[back to top]


In vitro DNA adenine methyltransferase activity has been demonstrated for YhdJ; overexpression of YhdJ leads to protection of chromosomal DNA from NsiI digestion, but DNA from wild type cells is not protected (Broadbent (2007). DNA from a DNA methyltransferase deficient strain (dam-, dcm-, EcoK-) does not react with anti-N6-methylA or anti-N4-methylC antibodies when YhdJ is expressed from the pBR322 Tet promoter; the yhdJ-containing pBR322 derivative was not resistant to a variety of restriction (personal communication: R. Vaisvila, S. Stickel and R.J. Roberts, unpublished results, April, 2006). The Kossykh (2004) report describing yhdJ as ccrM, an adenine methyltransferase, has been retracted.[4]



References

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  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.