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{{Tab On|Quickview|gadE}}{{Tab|Gene|gadE}}{{Tab|Gene Product(s)|gadE}}{{Tab|Expression|gadE}}{{Tab|Evolution|gadE}}{{Tab|On One Page|gadE}}{{TabsBottom}}
{{Tab On|Quickview|gadE}}{{Tab|Gene|gadE}}{{Tab|Gene Product(s)|gadE}}{{Tab|Expression|gadE}}{{Tab|Evolution|gadE}}{{Tab|On One Page|gadE}}{{TabsBottom}}
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!{{table_heading_style}} |Gene Name
!align=left {{table_heading_style}} |Standard Name
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[[gadE:Gene|''gadE]]'' (synonyms: ''ECK3496, b3512, JW3480, yhiE, yhiT'')<ref name='LIB:Riley_2006'/>
''gadE''
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!{{table_heading_style}} |Product(s)  
!align=left {{table_heading_style}} |Gene Synonym(s)
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[[gadE:Gene_Product(s)|GadE product]]<ref name='LIB:Riley_2006'/>: DNA-binding transcriptional activator product, B3512 product, YhiT product, YhiE product, acid-responsive regulator of gadA and gadBC product
''ECK3496, b3512, JW3480, yhiE, yhiT''<ref name='LIB:Riley_2006'/>, yhiT''
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!{{table_heading_style}} |Description
!align=left {{table_heading_style}} |Product Desc.
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GadE transcriptional activator<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>  
GadE transcriptional activator<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>


Transcriptional regulator of the gadABC operon<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Product Synonyms(s)
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''DNA-binding transcriptional activator<ref name='LIB:Riley_2006'/>, B3512<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YhiT<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YhiE<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, GadE<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, acid-responsive regulator of gadA and gadBC<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK3496, JW3480, yhiE, yhiT, b3512''
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!align=left {{table_heading_style}} |Function from GO
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<GO_nr />
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!{{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Knock-Out Phenotype
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Sensitive to pH below pH 2.5
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!{{table_heading_style}} |Regulation/Expression
!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:gadE|gadE]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:gadE|gadE]]<ref name='LIB:EcoCyc10.6'/>  
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!{{table_heading_style}} |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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Activated by EvgA, YdeO, GadX, GadW, GadE, MnmE(indirect?)
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!align=left {{table_heading_style}} |Quick Links
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[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=gadE&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG11544]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120001498&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=gadE&loc=MG1655%3A3656389..3656916,W3110%3A3982049..3981522,DH10B%3A3754134..3754661,BW2952%3A3544883..3545410]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=3544883&end=3545410&gene=gadE&aa=miflmtkdsfllqgfwqlkdnhemikinslseikkvgnkpfkviidtyhnhildeeaikflekldaeriivlapyhisklkakapiyfvsrkesiknlleitygkhlphknsqlcfshnqfkimqlilknknesnitstlnisqqtlkiqkfnimyklklrrmsdivtlgitsyf]]&nbsp;&nbsp;  [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=gadE+AND+escherichia+coli]]&nbsp;&nbsp;  [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=gadE]]&nbsp;&nbsp;


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==Notes==
===Notes===
{{BacktoTop}}
 
GadE overexpression confers acid resistance.  GadE is induced by YdeO overexpression.  GadE is in the EvgAS regulon.  GadE is a LuxR family regulator.  GadE is possibly involved in the regulation of type III secretion systems in enterohemorrhagic E. coli O157:H7. Required for stationary phase-induced, pH 5.5 growth medium-induced, and EvgA-induced acid resistance<ref name='LIB:EcoGene'/>
 




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==References==
==References==
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Latest revision as of 21:50, 27 May 2013

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Standard Name

gadE

Gene Synonym(s)

ECK3496, b3512, JW3480, yhiE, yhiT[1], yhiT

Product Desc.

GadE transcriptional activator[2][3]

Transcriptional regulator of the gadABC operon[4]

Product Synonyms(s)

DNA-binding transcriptional activator[1], B3512[2][1], YhiT[2][1], YhiE[2][1], GadE[2][1], acid-responsive regulator of gadA and gadBC[2][1] , ECK3496, JW3480, yhiE, yhiT, b3512

Function from GO

<GO_nr />

Knock-Out Phenotype

Sensitive to pH below pH 2.5

Regulation/Expression

transcription unit(s): gadE[2]

Regulation/Activity

Activated by EvgA, YdeO, GadX, GadW, GadE, MnmE(indirect?)

Quick Links



        

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See Help:Quickview for help with entering information in the Quickview table.

Notes

[back to top]


GadE overexpression confers acid resistance. GadE is induced by YdeO overexpression. GadE is in the EvgAS regulon. GadE is a LuxR family regulator. GadE is possibly involved in the regulation of type III secretion systems in enterohemorrhagic E. coli O157:H7. Required for stationary phase-induced, pH 5.5 growth medium-induced, and EvgA-induced acid resistance[4]



References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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