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{{Tab On|Quickview|surE}}{{Tab|Gene|surE}}{{Tab|Gene Product(s)|surE}}{{Tab|Expression|surE}}{{Tab|Evolution|surE}}{{Tab|On One Page|surE}}{{TabsBottom}}
{{Tab On|Quickview|surE}}{{Tab|Gene|surE}}{{Tab|Gene Product(s)|surE}}{{Tab|Expression|surE}}{{Tab|Evolution|surE}}{{Tab|On One Page|surE}}{{TabsBottom}}
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{|   id="L49b0260cb2c04"  class=" tableEdit New_Quickview_Table" 
 
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!{{table_heading_style}} |Gene Name
!align=left {{table_heading_style}} |Standard Name
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[[surE:Gene|''surE]]'' (synonyms: ''ECK2739, b2744, JW2714, ygbC'')<ref name='LIB:Riley_2006'/>
''surE''
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!{{table_heading_style}} |Product(s)  
!align=left {{table_heading_style}} |Gene Synonym(s)
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[[surE:Gene_Product(s)|SurE product]]<ref name='LIB:Riley_2006'/>: broad specificity 5'(3')-nucleotidase and polyphosphatase product, B2744 product, YgbC product
''ECK2739, b2744, JW2714, ygbC''<ref name='LIB:Riley_2006'/>, ygbC''
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!{{table_heading_style}} |Description
!align=left {{table_heading_style}} |Product Desc.
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broad specificity 5'(3')-nucleotidase and polyphosphatase<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>  
broad specificity 5'(3')-nucleotidase and polyphosphatase<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>


Nucleotidase, 5- or 3'-monophosphates; purine, pyrimidine, ribo- and deoxyribonucleotides all effectively hydrolyzed; short chain exopolyphosphatase<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Product Synonyms(s)
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''broad specificity 5'(3')-nucleotidase and polyphosphatase<ref name='LIB:Riley_2006'/>, B2744<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YgbC<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, SurE<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK2739, JW2714, ygbC, b2744''
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!align=left {{table_heading_style}} |Function from GO
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<GO_nr />
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!{{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!{{table_heading_style}} |Regulation/Expression
!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:surE-pcm|surE-pcm]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:surE-pcm|surE-pcm]]<ref name='LIB:EcoCyc10.6'/>  
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!{{table_heading_style}} |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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!align=left {{table_heading_style}} |Quick Links
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[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=surE&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG11817]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120001750&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=surE&loc=MG1655%3A2868296..2867535,W3110%3A2868930..2868169,DH10B%3A2960838..2960077,REL606%3A2765135..2764374,BW2952%3A2753347..2754108]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=2753347&end=2754108&gene=surE&aa=mrillsnddgvhapgiqtlakalrefadvqvvapdrnrsgasnsltlesslrtftfengdiavqmgtptdcvylgvnalmrprpdivvsginagpnlgddviysgtvaaamegrhlgfpalavsldghkhydtaaavtcsilralckeplrtgrilninvpdlpldqikgirvtrcgtrhpadqvipqqdprgntlywigppggkcdagpgtdfaavdegyvsitplhvdltahsaqdvvsdwlnsvgvgtqw]]&nbsp;&nbsp;  [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=surE+AND+escherichia+coli]]&nbsp;&nbsp;  [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=surE]]&nbsp;&nbsp;
 
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==Notes==
===Notes===
{{BacktoTop}}
 
A surE mutation is a specific suppressor of pcm stationary phase survival defects. The original surE mutant had a secondary rpoS mutation. The lack of survival in stationary phase was due to this cryptic rpoS mutation and clean surE mutants have no survival phenotype. SurE demonstrates nucleotidase preference for short chain substrates.  otherPDB (T. maritima): 1J9J, 1J9K, 1J9L, 1ILV.<ref name='LIB:EcoGene'/>
 




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==References==
==References==
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Latest revision as of 21:45, 27 May 2013

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Standard Name

surE

Gene Synonym(s)

ECK2739, b2744, JW2714, ygbC[1], ygbC

Product Desc.

broad specificity 5'(3')-nucleotidase and polyphosphatase[2][3]

Nucleotidase, 5- or 3'-monophosphates; purine, pyrimidine, ribo- and deoxyribonucleotides all effectively hydrolyzed; short chain exopolyphosphatase[4]

Product Synonyms(s)

broad specificity 5'(3')-nucleotidase and polyphosphatase[1], B2744[2][1], YgbC[2][1], SurE[2][1] , ECK2739, JW2714, ygbC, b2744

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): surE-pcm[2]

Regulation/Activity
Quick Links



        

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See Help:Quickview for help with entering information in the Quickview table.

Notes

[back to top]


A surE mutation is a specific suppressor of pcm stationary phase survival defects. The original surE mutant had a secondary rpoS mutation. The lack of survival in stationary phase was due to this cryptic rpoS mutation and clean surE mutants have no survival phenotype. SurE demonstrates nucleotidase preference for short chain substrates. otherPDB (T. maritima): 1J9J, 1J9K, 1J9L, 1ILV.[4]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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