plsY:Quickview: Difference between revisions

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*  ** PLEASE DON'T EDIT THIS TABLE DIRECTLY.  Use the edit table link under the table. **  
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!align=left {{table_heading_style}} |Standard Name
!align=left {{table_heading_style}} |Standard Name
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''plsY''  
''plsY''
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!align=left {{table_heading_style}} |Gene Synonym(s)
!align=left {{table_heading_style}} |Gene Synonym(s)
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''ECK3049, b3059, JW3031''<ref name='LIB:Riley_2006'/>, ygiH product
''ECK3049, b3059, JW3031'', ygiH<ref name='LIB:Riley_2006'/>, JW3031, ygiH''
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!align=left {{table_heading_style}} |Product Desc.
!align=left {{table_heading_style}} |Product Desc.
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!align=left {{table_heading_style}} |Product Synonyms(s)
!align=left {{table_heading_style}} |Product Synonyms(s)
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conserved inner membrane protein<ref name='LIB:Riley_2006'/>, B3059<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YgiH<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
''conserved inner membrane protein<ref name='LIB:Riley_2006'/>, B3059<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YgiH<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK3049, JW3031, ygiH, b3059''
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!align=left {{table_heading_style}} |Function from GO
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<GO_nr />
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!align=left {{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!align=left {{table_heading_style}} |Quick Links
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[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=ygiH&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG11674]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120001617&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=ygiH&loc=MG1655%3A3202716..3203333,W3110%3A3203350..3203967,DH10B%3A3300461..3301078,BW2952%3A3089864..3090481]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=3089864&end=3090481&gene=ygiH&aa=msaiapgmiliaylcgsissailvcrlcglpdprtsgsgnpgatnvlriggkgaavavlifdvlkgmlpvwgayelgvspfwlgliaiaaclghiwpvffgfkggkgvatafgaiapigwdltgvmagtwlltvllsgysslgaivsaliapfyvwwfkpqftfpvsmlsclillrhhdniqrlwrrqetkiwtkfkrkrekdpe]]&nbsp;&nbsp;  [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=ygiH+AND+escherichia+coli]]&nbsp;&nbsp;  [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=ygiH]]&nbsp;&nbsp;


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ygiH(plsY) and plsX are synthetic lethals and cannot be simultaneously deleted, implicating ygiH(plsY) involvement in phospholipid biosynthesis (Yoshimura, 2007). Homologous to the PlsY acylphosphate:glycerol-3-phosphate acyltransferase (UniProt: P0A4Q0) of S. pneumoniae, which identifies a function for the UPF0078 family (COG0344). S. pneumoniae PlsX and PlsY work together as a two-step glycerol-3-phosphate acylation, the first step in phosphatidic acid synthesis, an intermediate in phospholipid synthesis (Lu, 2006). PlsXY homologs are present in E. coli, but PlsXY apparently cannot substitute for the single step reaction catalyzed by PlsB, which is essental in E. coli.<ref name='LIB:EcoGene'/>
ygiH(plsY) and plsX are synthetic lethals and cannot be simultaneously deleted, implicating ygiH(plsY) involvement in phospholipid biosynthesis (Yoshimura, 2007). Homologous to the PlsY acylphosphate:glycerol-3-phosphate acyltransferase (UniProtKB:P0A4Q0) of S. pneumoniae, which identifies a function for the UPF0078 family (COG0344). S. pneumoniae PlsX and PlsY work together as a two-step glycerol-3-phosphate acylation, the first step in phosphatidic acid synthesis, an intermediate in phospholipid synthesis (Lu, 2006). PlsXY homologs are present in E. coli, but PlsXY apparently cannot substitute for the single step reaction catalyzed by PlsB, which is essental in E. coli.<ref name='LIB:EcoGene'/>






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==References==
==References==
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Latest revision as of 03:09, 30 June 2019

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Standard Name

plsY

Gene Synonym(s)

ECK3049, b3059, JW3031, ygiH[1], JW3031, ygiH

Product Desc.

conserved inner membrane protein[2][3]

Probable acylphosphate:glycerol-3-phosphate acyltransferase[4]

Product Synonyms(s)

conserved inner membrane protein[1], B3059[2][1], YgiH[2][1] , ECK3049, JW3031, ygiH, b3059

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): plsY[2]

Regulation/Activity
Quick Links



        

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Notes

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ygiH(plsY) and plsX are synthetic lethals and cannot be simultaneously deleted, implicating ygiH(plsY) involvement in phospholipid biosynthesis (Yoshimura, 2007). Homologous to the PlsY acylphosphate:glycerol-3-phosphate acyltransferase (UniProtKB:P0A4Q0) of S. pneumoniae, which identifies a function for the UPF0078 family (COG0344). S. pneumoniae PlsX and PlsY work together as a two-step glycerol-3-phosphate acylation, the first step in phosphatidic acid synthesis, an intermediate in phospholipid synthesis (Lu, 2006). PlsXY homologs are present in E. coli, but PlsXY apparently cannot substitute for the single step reaction catalyzed by PlsB, which is essental in E. coli.[4]



References

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  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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