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{{Tab On|Quickview|pagP}}{{Tab|Gene|pagP}}{{Tab|Gene Product(s)|pagP}}{{Tab|Expression|pagP}}{{Tab|Evolution|pagP}}{{Tab|On One Page|pagP}}{{TabsBottom}}
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!{{table_heading_style}} |Gene Name
!align=left {{table_heading_style}} |Standard Name
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[[pagP:Gene|''pagP]]'' (synonyms: ''crcA, ECK0615, b0622, JW0617, ybeG'')<ref name='LIB:Riley_2006'/><ref name='LIB:EcoCyc10.6'/>
''pagP''
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!{{table_heading_style}} |Product(s)  
!align=left {{table_heading_style}} |Gene Synonym(s)
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[[pagP:Gene_Product(s)|CrcA product]]<ref name='LIB:Riley_2006'/>: palmitoyl transferase for Lipid A<ref name='LIB:Riley_2006'/>, B0622<ref name='LIB:EcoCyc10.6'/>, YbeG<ref name='LIB:EcoCyc10.6'/>, CrcA<ref name='LIB:EcoCyc10.6'/>, PagP<ref name='LIB:EcoCyc10.6'/>, [[:Category:Complex:palmitoyl transferase for Lipid A|palmitoyl transferase for Lipid A]]<ref name='LIB:EcoCyc11.1'/>
''crcA, ECK0615, b0622, JW0617, ybeG''<ref name='LIB:Riley_2006'/><ref name='LIB:EcoCyc10.6'/>, ybeG''
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!{{table_heading_style}} |Description
!align=left {{table_heading_style}} |Product Desc.
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PagP monomer<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
PagP<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;


Component of [[:Category:Complex:palmitoyl transferase for Lipid A|palmitoyl transferase for Lipid A]]<ref name='LIB:EcoCyc11.1'/>


Lipid A biosynthesis, outer membrane; transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A (or its precursors); confers resistance to cationic antimicrobial peptides<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Product Synonyms(s)
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''palmitoyl transferase for Lipid A<ref name='LIB:Riley_2006'/>, B0622<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YbeG<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, CrcA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, PagP<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , crcA, ECK0615, JW0617, ybeG, b0622''
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!align=left {{table_heading_style}} |Function from GO
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<GO_nr />
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!{{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!{{table_heading_style}} |Regulation/Expression
!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:txn_units:pagP|pagP]]<ref name='LIB:EcoCyc10.6'/>, crcA  
transcription unit(s): [[:Category:Txn_unit:pagP|pagP]]<ref name='LIB:EcoCyc10.6'/>, crcA  
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!{{table_heading_style}} |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=pagP&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG12180]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120002073&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=pagP&loc=MG1655%3A655780..656340,W3110%3A656979..657539,BW2952%3A558540..559100]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=558540&end=559100&gene=pagP&aa=mnvskyvaifsfvfiqlisvgkvfanadewmttfreniaqtwqqpehydlyipaitwharfaydkektdrynerpwgggfglsrwdekgnwhglyamafkdswnkwepiagygwestwrpladenfhlglgftagvtardnwnyiplpvllplasvgygpvtfqmtyipgtynngnvyfawmrfqf]]&nbsp;&nbsp;  [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=pagP+AND+escherichia+coli]]&nbsp;&nbsp;  [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=pagP]]&nbsp;&nbsp;
 
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==Notes==
===Notes===
{{BacktoTop}}
 
Mg(2+) stimulon-PhoPQ regulon, EvgAS-PhoPQ cascade enhanced-expression subset. The  phoP-activation phenotype (PagP) was initially characterized in Salmonella then confirmed in E. coli (Jia, 2004). SignalP-NN incorrectly predicts a 27 aa signal peptide, but the verified cleavage site after 25 aa is predicted as a second possible cleavage site by SignalP-NN and as the only cleavage site by the more recent SignalP-HMM predictor (see SignalP button below).<ref name='LIB:EcoGene'/>
 




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==References==
==References==
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<references/>
<references/>
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Latest revision as of 21:47, 27 May 2013

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Standard Name

pagP

Gene Synonym(s)

crcA, ECK0615, b0622, JW0617, ybeG[1][2], ybeG

Product Desc.

PagP[2][3];

Component of palmitoyl transferase for Lipid A[3]

Lipid A biosynthesis, outer membrane; transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A (or its precursors); confers resistance to cationic antimicrobial peptides[4]

Product Synonyms(s)

palmitoyl transferase for Lipid A[1], B0622[2][1], YbeG[2][1], CrcA[2][1], PagP[2][1] , crcA, ECK0615, JW0617, ybeG, b0622

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): pagP[2], crcA

Regulation/Activity
Quick Links



        

See Help:Quickview for help with entering information in the Quickview table.

Notes

[back to top]


Mg(2+) stimulon-PhoPQ regulon, EvgAS-PhoPQ cascade enhanced-expression subset. The phoP-activation phenotype (PagP) was initially characterized in Salmonella then confirmed in E. coli (Jia, 2004). SignalP-NN incorrectly predicts a 27 aa signal peptide, but the verified cleavage site after 25 aa is predicted as a second possible cleavage site by SignalP-NN and as the only cleavage site by the more recent SignalP-HMM predictor (see SignalP button below).[4]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.