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{| | {| id="Z49aee2326a3d2" class=" tableEdit New_Quickview_Table" | ||
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!align=left {{table_heading_style}} |Standard Name | !align=left {{table_heading_style}} |Standard Name | ||
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''cobB'' | |||
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!align=left {{table_heading_style}} |Gene Synonym(s) | !align=left {{table_heading_style}} |Gene Synonym(s) | ||
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''ECK1106, b1120, JW1106, ycfY''<ref name='LIB:Riley_2006'/>, npdA, ycfY'' | |||
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!align=left {{table_heading_style}} |Product Desc. | !align=left {{table_heading_style}} |Product Desc. | ||
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protein deacetylase, Sir2 homolog<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/> | |||
Sirtuin lysine deacetylase for acetyl-CoA synthetase, NAD-dependent; partial cobalamin biosynthesis pathway present in E. coli<ref name='LIB:EcoGene'/> | |||
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!align=left {{table_heading_style}} |Product Synonyms(s) | !align=left {{table_heading_style}} |Product Synonyms(s) | ||
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''deacetylase of acetyl-CoA synthetase, NAD-dependent<ref name='LIB:Riley_2006'/>, B1120<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YcfY<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, CobB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK1106, JW1106, npdA, ycfY, b1120'' | |||
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!align=left {{table_heading_style}} |Function from GO | |||
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<GO_nr /> | |||
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!align=left {{table_heading_style}} |Knock-Out Phenotype | !align=left {{table_heading_style}} |Knock-Out Phenotype | ||
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!align=left {{table_heading_style}} |Regulation/Expression | !align=left {{table_heading_style}} |Regulation/Expression | ||
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transcription unit(s): [[:Category:Txn_unit:ycfX|ycfX]]<ref name='LIB:EcoCyc10.6'/> | |||
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!align=left {{table_heading_style}} |Regulation/Activity | !align=left {{table_heading_style}} |Regulation/Activity | ||
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!align=left {{table_heading_style}} |Quick Links | |||
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[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=cobB&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=G6577]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120003173&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=cobB&loc=MG1655%3A1178743..1179582,W3110%3A1181097..1181936,DH10B%3A1234188..1235027,REL606%3A1194892..1195731,BW2952%3A1082668..1083507]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=1082668&end=1083507&gene=cobB&aa=mlsrrghrlsrfrknkrrlrerlrqriffrdkvvpeamekprvlvltgagisaesgirtfraadglweehrvedvatpegfdrdpelvqafynarrrqlqqpeiqpnaahlalaklqdalgdrfllvtqnidnlheragntnvihmhgellkvrcsqsgqvldwtgdvtpedkchccqfpaplrphvvwfgemplgmdeiymalsmadifiaigtsghvypaagfvheaklhgahtvelnlepsqvgnefaekyygpasqvvpefvekllkglkagsia]] [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=cobB+AND+escherichia+coli]] [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=cobB]] | |||
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Latest revision as of 21:55, 27 May 2013
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
| Standard Name |
cobB |
|---|---|
| Gene Synonym(s) |
ECK1106, b1120, JW1106, ycfY[1], npdA, ycfY |
| Product Desc. |
protein deacetylase, Sir2 homolog[2][3] Sirtuin lysine deacetylase for acetyl-CoA synthetase, NAD-dependent; partial cobalamin biosynthesis pathway present in E. coli[4] |
| Product Synonyms(s) |
deacetylase of acetyl-CoA synthetase, NAD-dependent[1], B1120[2][1], YcfY[2][1], CobB[2][1] , ECK1106, JW1106, npdA, ycfY, b1120 |
| Function from GO |
<GO_nr /> |
| Knock-Out Phenotype | |
| Regulation/Expression | |
| Regulation/Activity | |
| Quick Links |
|
| edit table |
See Help:Quickview for help with entering information in the Quickview table.
Notes
CobB is primarily characterized in Salmonella (Starai, 2002). CobB may be responsible for additional lysine deacetylations since it is the only sirtuin homolog; Pat may be the general protein acetylase. A large number of lysines are acetylated and deacetylated in E. coli; presumably many or all of them by Pat/CobB (Yu, 2008; Zhang, 2008).[4]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.