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{{Tab On|Quickview|lsrA}}{{Tab|Gene|lsrA}}{{Tab|Gene Product(s)|lsrA}}{{Tab|Expression|lsrA}}{{Tab|Evolution|lsrA}}{{Tab|On One Page|lsrA}}{{TabsBottom}}
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!{{table_heading_style}} |Gene Name
!align=left {{table_heading_style}} |Standard Name
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[[lsrA:Gene|''lsrA]]'' (synonyms: ''ego, ECK1506, b1513, JW1506, ydeX'')<ref name='LIB:Riley_2006'/><ref name='LIB:EcoCyc10.6'/>
''lsrA''
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!{{table_heading_style}} |Product(s)  
!align=left {{table_heading_style}} |Gene Synonym(s)
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[[lsrA:Gene_Product(s)|Ego product]]<ref name='LIB:Riley_2006'/>: fused AI2 transporter subunits of ABC superfamily: ATP-binding components<ref name='LIB:Riley_2006'/>, B1513<ref name='LIB:EcoCyc10.6'/>, YdeX<ref name='LIB:EcoCyc10.6'/>, Ego<ref name='LIB:EcoCyc10.6'/>, [[:Category:Complex:LsrA/LsrC/LsrD/LsrB ABC transporter|LsrA/LsrC/LsrD/LsrB ABC transporter]]<ref name='LIB:EcoCyc10.6'/>
''ego, ECK1506, b1513, JW1506, ydeX''<ref name='LIB:Riley_2006'/><ref name='LIB:EcoCyc10.6'/>, lsrA, ydeX''
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!{{table_heading_style}} |Description
!align=left {{table_heading_style}} |Product Desc.
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LsrA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
LsrA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;


Component of [[:Category:Complex:LsrA/LsrC/LsrD/LsrB ABC transporter|LsrA/LsrC/LsrD/LsrB ABC transporter]]<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>


Autoinducer-2 (AI-2) uptake; essential for aerobic growth; upregulated in biofilms<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Product Synonyms(s)
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''fused AI2 transporter subunits of ABC superfamily: ATP-binding components<ref name='LIB:Riley_2006'/>, B1513<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YdeX<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Ego<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK1506, ego, JW1506, lsrA, ydeX, b1513''
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!align=left {{table_heading_style}} |Function from GO
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<GO_nr />
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!{{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!{{table_heading_style}} |Regulation/Expression
!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:txn_units:lsrACDBFG|lsrACDBFG]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:lsrACDBFG|lsrACDBFG]]<ref name='LIB:EcoCyc10.6'/>  
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!{{table_heading_style}} |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=lsrA&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=G6800]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120003389&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=lsrA&loc=MG1655%3A1599514..1601049,W3110%3A1603204..1604739,DH10B%3A1689139..1690674,BW2952%3A1491573..1493108]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=1491573&end=1493108&gene=lsrA&aa=mqtsdtralpllcarsvykqysgvnvlkgidftlhqgevhallggngagkstlmkiiagitpadsgtleiegnnyvrltpvhahqlgiylvpqepllfpslsikenilfglakkqlsmqkmknllaalgcqfdlhslagsldvadrqmveilrglmrdsrilildeptasltpaeterlfsrlqellatgvgivfishklpeirqiadrisvmrdgtialsgktselstddiiqaitpavrekslsasqklwlelpgnrpqhaagtpvltlenltgegfrnvsltlnageilglaglvgagrtelaetlyglrtlrggrimlngkeinklstgerllrglvylpedrqssglnldaslawnvcalthnlrgfwaktakdnatleryrralnikfnqpeqaartlsggnqqkiliakcleaspqvlivdeptrgvdvsarndiyqllrsiaaqnvavllissdleeielmadrvyvmhqgeithsalterdinvetimrvafgdsqrqeasc]]&nbsp;&nbsp;  [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=lsrA+AND+escherichia+coli]]&nbsp;&nbsp;  [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=lsrA]]&nbsp;&nbsp;
 
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==Notes==
===Notes===
{{BacktoTop}}
 
LsrA is paralogous to ribose transport ATPase RbsA. LsrA is in an operon regulated by LsrR and LuxS, through AI-2.  Biofilm microarray result was validated with RT-PCR. CRP regulon.<ref name='LIB:EcoGene'/>
 




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==References==
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Latest revision as of 21:48, 27 May 2013

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Standard Name

lsrA

Gene Synonym(s)

ego, ECK1506, b1513, JW1506, ydeX[1][2], lsrA, ydeX

Product Desc.

LsrA[2][3];

Component of LsrA/LsrC/LsrD/LsrB ABC transporter[2][3]

Autoinducer-2 (AI-2) uptake; essential for aerobic growth; upregulated in biofilms[4]

Product Synonyms(s)

fused AI2 transporter subunits of ABC superfamily: ATP-binding components[1], B1513[2][1], YdeX[2][1], Ego[2][1] , ECK1506, ego, JW1506, lsrA, ydeX, b1513

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): lsrACDBFG[2]

Regulation/Activity
Quick Links



        

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Notes

[back to top]


LsrA is paralogous to ribose transport ATPase RbsA. LsrA is in an operon regulated by LsrR and LuxS, through AI-2. Biofilm microarray result was validated with RT-PCR. CRP regulon.[4]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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