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{{Tab On|Quickview|sapD}}{{Tab|Gene|sapD}}{{Tab|Gene Product(s)|sapD}}{{Tab|Expression|sapD}}{{Tab|Evolution|sapD}}{{Tab|On One Page|sapD}}{{TabsBottom}}
{{Tab On|Quickview|sapD}}{{Tab|Gene|sapD}}{{Tab|Gene Product(s)|sapD}}{{Tab|Expression|sapD}}{{Tab|Evolution|sapD}}{{Tab|On One Page|sapD}}{{TabsBottom}}
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!{{table_heading_style}} |Gene Name
!align=left {{table_heading_style}} |Standard Name
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[[sapD:Gene|''sapD]]'' (synonyms: ''ECK1286, b1291, JW1284, trkE'')<ref name='LIB:Riley_2006'/>
''sapD''
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!{{table_heading_style}} |Product(s)  
!align=left {{table_heading_style}} |Gene Synonym(s)
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[[sapD:Gene_Product(s)|SapD product]]<ref name='LIB:Riley_2006'/>: predicted antimicrobial peptide transporter subunit<ref name='LIB:Riley_2006'/>, ATP-binding component of ABC superfamily<ref name='LIB:Riley_2006'/>, B1291<ref name='LIB:EcoCyc10.6'/>, TrkE<ref name='LIB:EcoCyc10.6'/>, SapD<ref name='LIB:EcoCyc10.6'/>, [[:Category:Complex:peptide uptake ABC transporter|peptide uptake ABC transporter]]<ref name='LIB:EcoCyc10.6'/>
''ECK1286, b1291, JW1284, trkE''<ref name='LIB:Riley_2006'/>, trkE''
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!{{table_heading_style}} |Description
!align=left {{table_heading_style}} |Product Desc.
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SapD<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
SapD<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;


Component of [[:Category:Complex:peptide uptake ABC transporter|peptide uptake ABC transporter]]<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>


Required for ATP-dependence of Trk K+ uptake systems; putative ABC transport system ATP-binding protein; unknown substrate(s);<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Product Synonyms(s)
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''predicted antimicrobial peptide transporter subunit<ref name='LIB:Riley_2006'/>, ATP-binding component of ABC superfamily<ref name='LIB:Riley_2006'/>, B1291<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, TrkE<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, SapD<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK1286, JW1284, trkE, b1291''
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!align=left {{table_heading_style}} |Function from GO
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<GO_nr />
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!{{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!{{table_heading_style}} |Regulation/Expression
!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:txn_units:sapF|sapF]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:sapF|sapF]]<ref name='LIB:EcoCyc10.6'/>  
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!{{table_heading_style}} |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=sapD&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG12304]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120002183&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=sapD&loc=MG1655%3A1351652..1350660,W3110%3A1355342..1354350,DH10B%3A1441048..1440056,REL606%3A1351997..1351005,BW2952%3A1241509..1242501]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=1241509&end=1242501&gene=sapD&aa=mplldirnltiefktgdewvkavdrvsmtltegeirglvgesgsgksliakaicgvnkdnwrvtadrmrfddidllrlsarerrklvghnvsmifqepqscldpservgrqlmqnipawtykgrwwqrfgwrkrraiellhrvgikdhkdamrsfpyeltegecqkvmiaialanqprlliadeptnsmepttqaqifrlltrlnqnsnttillishdlqmlsqwadkinvlycgqtvetapskelvtmphhpytqaliraipdfgsamphksrlntlpgaiplleqlpigcrlgprcpyaqrecivtprltgaknhlyachfplnmeke]]&nbsp;&nbsp;  [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=sapD+AND+escherichia+coli]]&nbsp;&nbsp;  [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=sapD]]&nbsp;&nbsp;
 
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==Notes==
===Notes===
{{BacktoTop}}
 
Overexpression causes filamentous biofilm formation. SapD(TrkE) is required for TrkAH activity and stimulates TrkAG transport rate (Bossemeyer, 1989; Dosch, 1991; Harms, 2001). Characterized initially in Salmonella. The proposal that the sap operon transports peptides (Groisman, 1992) has been challenged (Stumpe, 1997; Harms, 2001). SapA ATP-binding, but not hydrolysis, is required for stimulation of Trk (Harms, 2001).<ref name='LIB:EcoGene'/>
 




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==References==
==References==
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Latest revision as of 21:46, 27 May 2013

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Standard Name

sapD

Gene Synonym(s)

ECK1286, b1291, JW1284, trkE[1], trkE

Product Desc.

SapD[2][3];

Component of peptide uptake ABC transporter[2][3]

Required for ATP-dependence of Trk K+ uptake systems; putative ABC transport system ATP-binding protein; unknown substrate(s);[4]

Product Synonyms(s)

predicted antimicrobial peptide transporter subunit[1], ATP-binding component of ABC superfamily[1], B1291[2][1], TrkE[2][1], SapD[2][1] , ECK1286, JW1284, trkE, b1291

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): sapF[2]

Regulation/Activity
Quick Links



        

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Notes

[back to top]


Overexpression causes filamentous biofilm formation. SapD(TrkE) is required for TrkAH activity and stimulates TrkAG transport rate (Bossemeyer, 1989; Dosch, 1991; Harms, 2001). Characterized initially in Salmonella. The proposal that the sap operon transports peptides (Groisman, 1992) has been challenged (Stumpe, 1997; Harms, 2001). SapA ATP-binding, but not hydrolysis, is required for stimulation of Trk (Harms, 2001).[4]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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