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{{Tab On|Quickview|uup}}{{Tab|Gene|uup}}{{Tab|Gene Product(s)|uup}}{{Tab|Expression|uup}}{{Tab|Evolution|uup}}{{Tab|On One Page|uup}}{{TabsBottom}}
{{Tab On|Quickview|uup}}{{Tab|Gene|uup}}{{Tab|Gene Product(s)|uup}}{{Tab|Expression|uup}}{{Tab|Evolution|uup}}{{Tab|On One Page|uup}}{{TabsBottom}}
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|{{Sub}}[[Talk:{{PAGENAMEE}}| Suggestions]]
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!{{table_heading_style}} |Gene Name
!align=left {{table_heading_style}} |Standard Name
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[[uup:Gene|''uup]]'' (synonyms: ''ECK0940, b0949, JW0932, ycbH, ycbI, tex'')<ref name='LIB:Riley_2006'/><ref name='LIB:EcoCyc10.6'/>
''uup''
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!{{table_heading_style}} |Product(s)  
!align=left {{table_heading_style}} |Gene Synonym(s)
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[[uup:Gene_Product(s)|Uup product]]<ref name='LIB:Riley_2006'/>: fused predicted transporter subunits of ABC superfamily: ATP-binding components<ref name='LIB:Riley_2006'/>, B0949<ref name='LIB:EcoCyc10.6'/>, YcbH<ref name='LIB:EcoCyc10.6'/>, YcbI<ref name='LIB:EcoCyc10.6'/>, Uup<ref name='LIB:EcoCyc10.6'/>, Tex<ref name='LIB:EcoCyc10.6'/>
''ECK0940, b0949, JW0932, ycbH, ycbI, tex''<ref name='LIB:Riley_2006'/><ref name='LIB:EcoCyc10.6'/>
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!{{table_heading_style}} |Description
!align=left {{table_heading_style}} |Product Desc.
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ATP-binding protein with possible role in replication<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
ATP-binding protein with possible role in replication<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>


 
DNA-binding ATPase involved in replication; cytosolic; mutant displays an increased frequency of precise excision of transposons and defective growth of bacteriophage Mu<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Product Synonyms(s)
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''fused predicted transporter subunits of ABC superfamily: ATP-binding components<ref name='LIB:Riley_2006'/>, B0949<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YcbH<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YcbI<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Uup<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Tex<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK0940, JW0932, ycbH, ycbI, b0949''
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!align=left {{table_heading_style}} |Function from GO
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<GO_nr />
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!{{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!{{table_heading_style}} |Regulation/Expression
!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:txn_units:rlmL-uup|rlmL-uup]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:rlmL-uup|rlmL-uup]]<ref name='LIB:EcoCyc10.6'/>  
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!{{table_heading_style}} |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=uup&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=G6489]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120003089&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=uup&loc=MG1655%3A1009187..1011094,W3110%3A1010386..1012293,DH10B%3A1063115..1065022,REL606%3A1027055..1028962,BW2952%3A912155..914062]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=912155&end=914062&gene=uup&aa=mslismhgawlsfsdaplldnaelhiednervclvgrngagkstlmkilnreqglddgriiyeqdlivarlqqdpprnvegsvydfvaegieeqaeylkryhdisrlvmndpseknlnelakvqeqldhhnlwqlenrinevlaqlgldpnvalsslsggwlrkaalgralvsnprvllldeptnhldietidwlegflktfngtiifishdrsfirnmatrivdldrgklvtypgnydqyllekeealrveelqnaefdrklaqeevwirqgikarrtrnegrvralkamrrergerrevmgtakmqveeasrsgkivfemedvcyqvngkqlvkdfsaqvlrgdkialigpngcgkttllklmlgqlqadsgrihvgtklevayfdqhraeldpdktvmdnlaegkqevmvngkprhvlgylqdflfhpkramtpvralsggernrlllarlflkpsnllildeptndldvetlelleelidsyqgtvllvshdrqfvdntvtecwifegggkigryvggyhdargqqeqyvalkqpavkkteeaaaakaetvkrsssklsyklqreleqlpqlledleaklealqtqvadasffsqpheqtqkvladmaaaeqeleqaferweylealkngg]]&nbsp;&nbsp;  [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=uup+AND+escherichia+coli]]&nbsp;&nbsp;  [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=uup]]&nbsp;&nbsp;
 
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==Notes==
===Notes===
{{BacktoTop}}
 
Has two ABC ATPase domains; ATPase activity is essential for function. A C-terminal domain of the protein displays predicted structural homology with the Little Finger domain of Y family DNA polymerases and is involved in DNA binding.<ref name='LIB:EcoGene'/>
 
Similar to yeast proteins involved in ribosomal function and assembly.
 
 
 
 




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==References==
==References==
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Latest revision as of 21:45, 27 May 2013

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Standard Name

uup

Gene Synonym(s)

ECK0940, b0949, JW0932, ycbH, ycbI, tex[1][2]

Product Desc.

ATP-binding protein with possible role in replication[2][3]

DNA-binding ATPase involved in replication; cytosolic; mutant displays an increased frequency of precise excision of transposons and defective growth of bacteriophage Mu[4]

Product Synonyms(s)

fused predicted transporter subunits of ABC superfamily: ATP-binding components[1], B0949[2][1], YcbH[2][1], YcbI[2][1], Uup[2][1], Tex[2][1] , ECK0940, JW0932, ycbH, ycbI, b0949

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): rlmL-uup[2]

Regulation/Activity
Quick Links



        

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Notes

[back to top]


Has two ABC ATPase domains; ATPase activity is essential for function. A C-terminal domain of the protein displays predicted structural homology with the Little Finger domain of Y family DNA polymerases and is involved in DNA binding.[4]

Similar to yeast proteins involved in ribosomal function and assembly.





References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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