mfd:Quickview: Difference between revisions

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!{{table_heading_style}} |Gene Name
!align=left {{table_heading_style}} |Standard Name
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[[mfd:Gene|''mfd]]'' (synonyms: ''ECK1100, b1114, JW1100'')<ref name='LIB:Riley_2006'/>
''mfd''
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!{{table_heading_style}} |Product(s)  
!align=left {{table_heading_style}} |Gene Synonym(s)
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[[mfd:Gene_Product(s)|Mfd product]]<ref name='LIB:Riley_2006'/>: transcription-repair coupling factor product, B1114 product, TRCF product
''ECK1100, b1114, JW1100''<ref name='LIB:Riley_2006'/>, JW1100''
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!{{table_heading_style}} |Description
!align=left {{table_heading_style}} |Product Desc.
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transcription-repair coupling factor<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>  
transcription-repair coupling factor<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>


Transcription repair coupling factor<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Product Synonyms(s)
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''transcription-repair coupling factor<ref name='LIB:Riley_2006'/>, B1114<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Mfd<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, TRCF<ref name='LIB:EcoCyc11.1'/><ref name='LIB:Riley_2006'/> , ECK1100, JW1100, b1114''
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!align=left {{table_heading_style}} |Function from GO
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<GO_nr />
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!{{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!{{table_heading_style}} |Regulation/Expression
!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:mfd|mfd]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:mfd|mfd]]<ref name='LIB:EcoCyc10.6'/>  
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!{{table_heading_style}} |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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!align=left {{table_heading_style}} |Quick Links
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[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=mfd&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG11619]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120001567&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=mfd&loc=MG1655%3A1173187..1169741,W3110%3A1175541..1172095,DH10B%3A1228632..1225186,REL606%3A1188559..1185113,BW2952%3A1073666..1077112]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=1073666&end=1077112&gene=mfd&aa=mpeqyrytlpvkageqrllgeltgaacatlvaeiaerhagpvvliapdmqnalrlhdeisqftdqmvmnladwetlpydsfsphqdiissrlstlyqlptmqrgvlivpvntlmqrvcphsflhghalvmkkgqrlsrdalrtqldsagyrhvdqvmehgeyatrgalldlfpmgselpyrldffddeidslrvfdvdsqrtleeveainllpahefptdkaaielfrsqwrdtfevkrdpehiyqqvskgtlpagieywqplffseplpplfsyfpantllvntgdletsaerfqadtlarfenrgvdpmrpllppqslwlrvdelfselknwprvqlktehlptkaananlgfqklpdlavqaqqkapldalrkfletfdgpvvfsvesegrrealgellarikiapqrimrldeasdrgrylmigaaehgfvdtvrnlalicesdllgervarrrqdsrrtinpdtlirnlaelhigqpvvhlehgvgryagmttleaggitgeylmltyandaklyvpvsslhlisryaggaeenaplhklggdawsrarqkaaekvrdvaaelldiyaqraakegfafkhdreqyqlfcdsfpfettpdqaqainavlsdmcqplamdrlvcgdvgfgktevamraaflavdnhkqvavlvpttllaqqhydnfrdrfanwpvriemisrfrsakeqtqilaevaegkidiligthkllqsdvkfkdlgllivdeehrfgvrhkerikamranvdiltltatpiprtlnmamsgmrdlsiiatpparrlavktfvreydsmvvreailreilrggqvyylyndveniqkaaerlaelvpeariaighgqmrerelervmndfhhqrfnvlvcttiietgidiptantiiieradhfglaqlhqlrgrvgrshhqayawlltphpkamttdaqkrleaiasledlgagfalathdleirgagellgeeqsgsmetigfslymellenavdalkagrepsledltsqqtevelrmpsllpddfipdvntrlsfykriasakteneleeikvelidrfgllpdpartlldiarlrqqaqklgirklegnekggviefaeknhvnpawligllqkqpqhyrldgptrlkfiqdlserktriewvrqfmreleenaia]]&nbsp;&nbsp;  [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=mfd+AND+escherichia+coli]]&nbsp;&nbsp;  [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=mfd]]&nbsp;&nbsp;
 
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===Notes===
===Notes===
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Mfd dissociates transcription elongation complexes blocked at nonpairing lesions and mediates recruitment of DNA repair proteins.  Arrested (backtracked) RNAP complexes are are also rescued by Mfd promoting forward translocation. Mfd structure resembles UvrB, including UvrA binding site, but no ATP-binding site.<ref name='LIB:EcoGene'/>




Latest revision as of 21:48, 27 May 2013

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Standard Name

mfd

Gene Synonym(s)

ECK1100, b1114, JW1100[1], JW1100

Product Desc.

transcription-repair coupling factor[2][3]

Transcription repair coupling factor[4]

Product Synonyms(s)

transcription-repair coupling factor[1], B1114[2][1], Mfd[2][1], TRCF[3][1] , ECK1100, JW1100, b1114

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): mfd[2]

Regulation/Activity
Quick Links



        

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Notes

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Mfd dissociates transcription elongation complexes blocked at nonpairing lesions and mediates recruitment of DNA repair proteins. Arrested (backtracked) RNAP complexes are are also rescued by Mfd promoting forward translocation. Mfd structure resembles UvrB, including UvrA binding site, but no ATP-binding site.[4]



References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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