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{{Tab On|Quickview|dppA}}{{Tab|Gene|dppA}}{{Tab|Gene Product(s)|dppA}}{{Tab|Expression|dppA}}{{Tab|Evolution|dppA}}{{Tab|On One Page|dppA}}{{TabsBottom}}
{{Tab On|Quickview|dppA}}{{Tab|Gene|dppA}}{{Tab|Gene Product(s)|dppA}}{{Tab|Expression|dppA}}{{Tab|Evolution|dppA}}{{Tab|On One Page|dppA}}{{TabsBottom}}
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!{{table_heading_style}} |Gene Name
!align=left {{table_heading_style}} |Standard Name
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[[dppA:Gene|''dppA]]'' (synonyms: ''ECK3531, b3544, JW3513, alu, dpp, fpp'')<ref name='LIB:Riley_2006'/>
''dppA''
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!{{table_heading_style}} |Product(s)  
!align=left {{table_heading_style}} |Gene Synonym(s)
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[[dppA:Gene_Product(s)|DppA product]]<ref name='LIB:Riley_2006'/>: dipeptide transporter<ref name='LIB:Riley_2006'/>, periplasmic-binding component of ABC superfamily<ref name='LIB:Riley_2006'/>, B3544<ref name='LIB:EcoCyc10.6'/>, Fpp<ref name='LIB:EcoCyc10.6'/>, Dpp<ref name='LIB:EcoCyc10.6'/>, Alu<ref name='LIB:EcoCyc10.6'/>, DppA<ref name='LIB:EcoCyc10.6'/>, [[:Category:Complex:dipeptide ABC transporter|dipeptide ABC transporter]]<ref name='LIB:EcoCyc10.6'/>
''ECK3531, b3544, JW3513, alu, dpp, fpp''<ref name='LIB:Riley_2006'/>, fpp''
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!{{table_heading_style}} |Description
!align=left {{table_heading_style}} |Product Desc.
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DppA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
DppA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;


Component of [[:Category:Complex:dipeptide ABC transporter|dipeptide ABC transporter]]<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>


Dipeptide/heme transport, periplasmic binding protein; recognition for transport and chemotaxis<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Product Synonyms(s)
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''dipeptide transporter<ref name='LIB:Riley_2006'/>, periplasmic-binding component of ABC superfamily<ref name='LIB:Riley_2006'/>, B3544<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Fpp<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Dpp<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Alu<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, DppA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , alu, dpp, ECK3531, fpp, JW3513, b3544''
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!align=left {{table_heading_style}} |Function from GO
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<GO_nr />
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!{{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!{{table_heading_style}} |Regulation/Expression
!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:txn_units:dppABCDF|dppABCDF]]<ref name='LIB:EcoCyc10.6'/>, dpp, dppABCDE  
transcription unit(s): [[:Category:Txn_unit:dppABCDF|dppABCDF]]<ref name='LIB:EcoCyc10.6'/>, dpp, dppABCDE  
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!{{table_heading_style}} |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=dppA&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG10248]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120000242&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=dppA&loc=MG1655%3A3705728..3704121,W3110%3A3932710..3934317,DH10B%3A3803473..3801866,REL606%3A3638163..3636556,BW2952%3A3592615..3594222]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=3592615&end=3594222&gene=dppA&aa=mrislkksgmlklglslvamtvaasvqaktlvycsegspegfnpqlftsgttydassvplynrlvefkigttevipglaekwevsedgktytfhlrkgvkwhdnkefkptrelnaddvvfsfdrqknaqnpyhkvsggsyeyfegmglpelisevkkvddntvqfvltrpeapfladlamdfasilskeyadammkagtpekldlnpigtgpfqlqqyqkdsrirykafdgywgtkpqidtlvfsitpdasvryaklqknecqvmpypnpadiarmkqdksinlmempglnvgylsynvqkkplddvkvrqaltyavnkdaiikavyqgagvsaknlipptmwgynddvqdytydpekakallkeaglekgfsidlwampvqrpynpnarrmaemiqadwakvgvqakivtyewgeylkrakdgehqtvmmgwtgdngdpdnffatlfscaaseqgsnyskwcykpfedliqparatddhnkrvelykqaqvvmhdqapaliiahstvfepvrkevkgyvvdplgkhhfenvsie]]&nbsp;&nbsp;  [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=dppA+AND+escherichia+coli]]&nbsp;&nbsp;  [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=dppA]]&nbsp;&nbsp;
 
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==Notes==
===Notes===
{{BacktoTop}}
 
DppA binds dipeptides and heme, and mediates chemotaxis to dipeptides through the Tap chemoreceptor. E. coli does not normally use exogeneous heme, but heme can be utilized if a foreign OM heme receptor is expressed in E. coli; heme and dipeptides compete for the same binding site; MppA is an alternative heme periplasmic binding protein; MppA or DppA is required for the uptake of 5-aminolevulinic acid (Letoffe, 2006). After four hours of Zn(II) stress, DppA protein levels decreased (Easton, 2006).<ref name='LIB:EcoGene'/>
 




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==References==
==References==
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Latest revision as of 21:51, 27 May 2013

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Standard Name

dppA

Gene Synonym(s)

ECK3531, b3544, JW3513, alu, dpp, fpp[1], fpp

Product Desc.

DppA[2][3];

Component of dipeptide ABC transporter[2][3]

Dipeptide/heme transport, periplasmic binding protein; recognition for transport and chemotaxis[4]

Product Synonyms(s)

dipeptide transporter[1], periplasmic-binding component of ABC superfamily[1], B3544[2][1], Fpp[2][1], Dpp[2][1], Alu[2][1], DppA[2][1] , alu, dpp, ECK3531, fpp, JW3513, b3544

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): dppABCDF[2], dpp, dppABCDE

Regulation/Activity
Quick Links



        

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Notes

[back to top]


DppA binds dipeptides and heme, and mediates chemotaxis to dipeptides through the Tap chemoreceptor. E. coli does not normally use exogeneous heme, but heme can be utilized if a foreign OM heme receptor is expressed in E. coli; heme and dipeptides compete for the same binding site; MppA is an alternative heme periplasmic binding protein; MppA or DppA is required for the uptake of 5-aminolevulinic acid (Letoffe, 2006). After four hours of Zn(II) stress, DppA protein levels decreased (Easton, 2006).[4]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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