dctR:Quickview: Difference between revisions

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{{Tab On|Quickview|dctR}}{{Tab|Gene|dctR}}{{Tab|Gene Product(s)|dctR}}{{Tab|Expression|dctR}}{{Tab|Evolution|dctR}}{{Tab|On One Page|dctR}}{{TabsBottom}}
{{Tab On|Quickview|dctR}}{{Tab|Gene|dctR}}{{Tab|Gene Product(s)|dctR}}{{Tab|Expression|dctR}}{{Tab|Evolution|dctR}}{{Tab|On One Page|dctR}}{{TabsBottom}}
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!{{table_heading_style}} |Gene Name
!align=left {{table_heading_style}} |Standard Name
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[[dctR:Gene|''dctR]]'' (synonyms: ''yhiF, ECK3491, b3507, JW3475'')<ref name='LIB:Riley_2006'/><ref name='LIB:EcoCyc10.6'/>
''dctR''
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!{{table_heading_style}} |Product(s)  
!align=left {{table_heading_style}} |Gene Synonym(s)
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[[dctR:Gene_Product(s)|YhiF product]]<ref name='LIB:Riley_2006'/>: predicted DNA-binding ranscriptional regulator<ref name='LIB:Riley_2006'/>, B3507<ref name='LIB:EcoCyc10.6'/>, DctR<ref name='LIB:EcoCyc10.6'/>, YhiF<ref name='LIB:EcoCyc10.6'/>
''yhiF, ECK3491, b3507, JW3475''<ref name='LIB:Riley_2006'/><ref name='LIB:EcoCyc10.6'/>, JW3475''
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!{{table_heading_style}} |Description
!align=left {{table_heading_style}} |Product Desc.
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protein involved in metabolism of C4-dicarboxylates<ref name='LIB:EcoCyc10.6'/>predicted DNA-binding transcriptional regulator<ref name='LIB:EcoCyc11.1'/>
protein involved in metabolism of C4-dicarboxylates<ref name='LIB:EcoCyc10.6'/>; predicted DNA-binding transcriptional regulator<ref name='LIB:EcoCyc11.1'/>
 


Probable repressor of dctA dicarboxylate transporter gene<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Product Synonyms(s)
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''predicted DNA-binding ranscriptional regulator<ref name='LIB:Riley_2006'/>, B3507<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, DctR<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YhiF<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK3491, JW3475, yhiF, b3507''
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!align=left {{table_heading_style}} |Function from GO
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<GO_nr />
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!{{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!{{table_heading_style}} |Regulation/Expression
!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:txn_units:yhiF|yhiF]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:yhiF|yhiF]]<ref name='LIB:EcoCyc10.6'/>  
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!{{table_heading_style}} |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=dctR&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG11889]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120001819&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=dctR&loc=MG1655%3A3652706..3653236,W3110%3A3985732..3985202,BW2952%3A3541200..3541730]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=3541200&end=3541730&gene=dctR&aa=mfliitrdtmfftamknilskgnvvhiqneeeidvmlhqnafviidtlmnnvfhsnfltqierlkpvhviifspfnikrclgkvpvtfvprtitiidfvalingsycsvpeaavslsrkqhqvlscianqmttedileklkislktfychkhnimmilnlkrinelvrhqhidylv]]&nbsp;&nbsp;  [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=dctR+AND+escherichia+coli]]&nbsp;&nbsp;  [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=dctR]]&nbsp;&nbsp;
 
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==Notes==
===Notes===
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DctR is in the EvgAS regulon.  Mutation reverses succinate growth defect of an atp operon deletion, as does a DctA overproducer.  Overproduced DctR blocks growth on succinate, presumably by repressing dctA.  Overexpression of DctR causes filamentous biofilm formation.  DctR is a member of the LuxR family of regulatory proteins and is homologous to the DctR response regulator of R. capsulatus.  DctR is possibly involved in the regulation of type III secretion systems in enterohemorrhagic E. coli O157:H7.<ref name='LIB:EcoGene'/>
 




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==References==
==References==
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Latest revision as of 21:51, 27 May 2013

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Standard Name

dctR

Gene Synonym(s)

yhiF, ECK3491, b3507, JW3475[1][2], JW3475

Product Desc.

protein involved in metabolism of C4-dicarboxylates[2]; predicted DNA-binding transcriptional regulator[3]

Probable repressor of dctA dicarboxylate transporter gene[4]

Product Synonyms(s)

predicted DNA-binding ranscriptional regulator[1], B3507[2][1], DctR[2][1], YhiF[2][1] , ECK3491, JW3475, yhiF, b3507

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): yhiF[2]

Regulation/Activity
Quick Links



        

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Notes

[back to top]


DctR is in the EvgAS regulon. Mutation reverses succinate growth defect of an atp operon deletion, as does a DctA overproducer. Overproduced DctR blocks growth on succinate, presumably by repressing dctA. Overexpression of DctR causes filamentous biofilm formation. DctR is a member of the LuxR family of regulatory proteins and is homologous to the DctR response regulator of R. capsulatus. DctR is possibly involved in the regulation of type III secretion systems in enterohemorrhagic E. coli O157:H7.[4]



References

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  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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