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{{Tab On|Quickview|acrE}}{{Tab|Gene|acrE}}{{Tab|Gene Product(s)|acrE}}{{Tab|Expression|acrE}}{{Tab|Evolution|acrE}}{{Tab|On One Page|acrE}}{{TabsBottom}}
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!{{table_heading_style}} |Gene Name
!align=left {{table_heading_style}} |Standard Name
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[[acrE:Gene|''acrE]]'' (synonyms: ''ECK3252, b3265, JW3233, envC, G7979'')<ref name='LIB:Riley_2006'/><ref name='LIB:EcoCyc10.6'/>
''acrE''
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!{{table_heading_style}} |Product(s)  
!align=left {{table_heading_style}} |Gene Synonym(s)
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[[acrE:Gene_Product(s)|AcrE product]]<ref name='LIB:Riley_2006'/>: cytoplasmic membrane lipoprotein<ref name='LIB:Riley_2006'/>, B3265<ref name='LIB:EcoCyc10.6'/>, EnvC<ref name='LIB:EcoCyc10.6'/>, AcrE<ref name='LIB:EcoCyc10.6'/>, [[:Category:Complex:AcrEF-TolC Multidrug Efflux Transport System|AcrEF-TolC Multidrug Efflux Transport System]]<ref name='LIB:EcoCyc11.1'/>
''ECK3252, b3265, JW3233, G7979''<ref name='LIB:Riley_2006'/><ref name='LIB:EcoCyc10.6'/>, envC''
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!{{table_heading_style}} |Description
!align=left {{table_heading_style}} |Product Desc.
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transmembrane protein affects septum formation and cell membrane permeability<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
transmembrane protein affects septum formation and cell membrane permeability<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;


Component of [[:Category:Complex:AcrEF-TolC Multidrug Efflux Transport System|AcrEF-TolC Multidrug Efflux Transport System]]<ref name='LIB:EcoCyc11.1'/>


AcrEF-TolC efflux pump, multidrug/solvent resistance; membrane-fusion lipoprotein<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Product Synonyms(s)
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''cytoplasmic membrane lipoprotein<ref name='LIB:Riley_2006'/>, B3265<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, AcrE<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK3252, envC, JW3233, b3265''
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!align=left {{table_heading_style}} |Function from GO
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<GO_nr />
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!{{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!{{table_heading_style}} |Regulation/Expression
!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:txn_units:acrEF|acrEF]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:acrEF|acrEF]]<ref name='LIB:EcoCyc10.6'/>  
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!{{table_heading_style}} |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=acrE&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG10266]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120000260&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=acrE&loc=MG1655%3A3411886..3413043,W3110%3A3413719..3414876,REL606%3A3341755..3342912,DH10B%3A3509631..3510788,BW2952%3A3299034..3300191]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=3299034&end=3300191&gene=acrE&aa=mtkharffllpsfilisaaliagcndkgeekahvgepqvtvhivktaplevktelpgrtnayriaevrpqvsgivlnrnftegsdvqagqslyqidpatyqanydsakgelakseaaaaiahltvkryvplvgtkyisqqeydqaiadarqadaaviaakatvesarinlaytkvtapisgrigkstvtegalvtngqttelatvqqldpiyvdvtqssndfmrlkqsveqgnlhkenatsnvelvmengqtyplkgtlqfsdvtvdestgsitlravfpnpqhtllpgmfvraridegvqpdailipqqgvsrtprgdatvlivndksqvearpvvasqaigdkwliseglksgdqvivsglqkarpgeqvkattdtpadtask]]&nbsp;&nbsp;  [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=acrE+AND+escherichia+coli]]&nbsp;&nbsp;  [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=acrE]]&nbsp;&nbsp;
 
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==Notes==
===Notes===
{{BacktoTop}}
 
AcrE is attached to the inner membrane. AcrEF confers resistance to nalidixic acid, acriflavin, indole and solvents. acrE is an acrA paralog. May have role in cell division. First 23 aa are a type II signal peptide.<ref name='LIB:EcoGene'/>
 




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==References==
==References==
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Latest revision as of 21:53, 27 May 2013

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Standard Name

acrE

Gene Synonym(s)

ECK3252, b3265, JW3233, G7979[1][2], envC

Product Desc.

transmembrane protein affects septum formation and cell membrane permeability[2][3];

Component of AcrEF-TolC Multidrug Efflux Transport System[3]

AcrEF-TolC efflux pump, multidrug/solvent resistance; membrane-fusion lipoprotein[4]

Product Synonyms(s)

cytoplasmic membrane lipoprotein[1], B3265[2][1], AcrE[2][1] , ECK3252, envC, JW3233, b3265

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): acrEF[2]

Regulation/Activity
Quick Links



        

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Notes

[back to top]


AcrE is attached to the inner membrane. AcrEF confers resistance to nalidixic acid, acriflavin, indole and solvents. acrE is an acrA paralog. May have role in cell division. First 23 aa are a type II signal peptide.[4]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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