hflC:Quickview: Difference between revisions

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*  ** PLEASE DON'T EDIT THIS TABLE DIRECTLY.  Use the edit table link under the table. **  
*  ** PLEASE DON'T EDIT THIS TABLE DIRECTLY.  Use the edit table link under the table. **  
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!align=left {{table_heading_style}} |Gene Synonym(s)
!align=left {{table_heading_style}} |Gene Synonym(s)
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''ECK4171, b4175, JW4133, hflA''<ref name='LIB:Riley_2006'/>
''ECK4171, b4175, JW4133, hflA''<ref name='LIB:Riley_2006'/>, hflA''
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!align=left {{table_heading_style}} |Product Desc.
!align=left {{table_heading_style}} |Product Desc.
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!align=left {{table_heading_style}} |Product Synonyms(s)
!align=left {{table_heading_style}} |Product Synonyms(s)
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modulator for HflB protease specific for phage lambda cII repressor product<ref name='LIB:Riley_2006'/>, B4175 product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, HflA product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, HflC product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
''modulator for HflB protease specific for phage lambda cII repressor<ref name='LIB:Riley_2006'/>, B4175<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, HflA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, HflC<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK4171, hflA, JW4133, b4175''
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!align=left {{table_heading_style}} |Function from GO
!align=left {{table_heading_style}} |Function from GO
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!align=left {{table_heading_style}} |Quick Links
!align=left {{table_heading_style}} |Quick Links
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[http://ecoliwiki.net/tools/display_dna.php?gene=hflC&loc=MG1655:4401323..4402327,W3110:4407980..4408984,REL606:4381455..4382459,DH10B:4501685..4502689 DNA display]&nbsp;&nbsp;&nbsp; [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=4501685&end=4502689&gene=hflC&aa=mrksviaiiiivlvvlymsvfvvkegergitlrfgkvlrdddnkplvyepglhfkipfietvkmldariqtmdnqadrfvtkekkdlivdsyikwrisdfsryylatgggdisqaevllkrkfsdrlrseigrldvkdivtdsrgrltlevrdalnsgsagtedevttpaadnaiaeaaervtaetkgkvpvinpnsmaalgievvdvrikqinlptevseaiynrmraereavarrhrsqgqeeaeklratadyevtrtlaeaerqgrimrgegdaeaaklfadafskdpdfyafirslrayensfsgnqdvmvmspdsdffrymktptsatr Protein display]&nbsp;&nbsp;&nbsp; [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=hflC+AND+escherichia+coli Pubmed(hflC)]&nbsp;&nbsp;&nbsp; [http://trimer.tamu.edu/cgi-bin/textpresso/dev/search?q=hflC Textpresso(hflC)]
[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=hflC&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG10435]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120000428&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=hflC&loc=MG1655%3A4401323..4402327,W3110%3A4407980..4408984,REL606%3A4381455..4382459,DH10B%3A4501685..4502689,BW2952%3A4340058..4341062]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=4340058&end=4341062&gene=hflC&aa=mrksviaiiiivlvvlymsvfvvkegergitlrfgkvlrdddnkplvyepglhfkipfietvkmldariqtmdnqadrfvtkekkdlivdsyikwrisdfsryylatgggdisqaevllkrkfsdrlrseigrldvkdivtdsrgrltlevrdalnsgsagtedevttpaadnaiaeaaervtaetkgkvpvinpnsmaalgievvdvrikqinlptevseaiynrmraereavarrhrsqgqeeaeklratadyevtrtlaeaerqgrimrgegdaeaaklfadafskdpdfyafirslrayensfsgnqdvmvmspdsdffrymktptsatr]]&nbsp;&nbsp; [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=hflC+AND+escherichia+coli]]&nbsp;&nbsp; [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=hflC]]&nbsp;&nbsp;


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Latest revision as of 21:54, 27 May 2013

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Standard Name

hflC

Gene Synonym(s)

ECK4171, b4175, JW4133, hflA[1], hflA

Product Desc.

regulator of FtsH protease[2][3];

Component of HflK-HflC complex; regulator of FtsH protease[3]; HflB, integral membrane ATP-dependent zinc metallopeptidase[3]

Membrane bound protease complex, with FtsH and HflK; regulates lysogeny; non-essential[4]

Product Synonyms(s)

modulator for HflB protease specific for phage lambda cII repressor[1], B4175[2][1], HflA[2][1], HflC[2][1] , ECK4171, hflA, JW4133, b4175

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): yjeFE-amiB-mutL-miaA-hfq-hflXKC[2], ORF55-ORF17-amiB-mutL-miaA-hfq-hflXKC

Regulation/Activity
Quick Links



        

edit table

See Help:Quickview for help with entering information in the Quickview table.

Notes

[back to top]


Gain-of-function alleles in hflC and hflK inhibit FtsH-mediated degradation of uncomplexed SecY protein and other membrane protein substrates. Null hflC or hflK alleles stabilize cytoplasmic substrate cII. hflCK is a multicopy suppressor of ftsH htpX double mutant. Serine protease-like motif in HflC not required for cII degradation. HflC and HflK have a periplasmic prohibitin homology (PHB) domain. HT_Cmplx45_Mem: HflC+HybC+BamB.[4]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 3.2 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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