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{{Tab On|Quickview|nrdD}}{{Tab|Gene|nrdD}}{{Tab|Gene Product(s)|nrdD}}{{Tab|Expression|nrdD}}{{Tab|Evolution|nrdD}}{{Tab|On One Page|nrdD}}{{TabsBottom}}
{{Tab On|Quickview|nrdD}}{{Tab|Gene|nrdD}}{{Tab|Gene Product(s)|nrdD}}{{Tab|Expression|nrdD}}{{Tab|Evolution|nrdD}}{{Tab|On One Page|nrdD}}{{TabsBottom}}
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!{{table_heading_style}} |Gene Name
!align=left {{table_heading_style}} |Standard Name
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[[nrdD:Gene|''nrdD]]'' (synonyms: ''ECK4233, b4238, JW4197'')<ref name='LIB:Riley_2006'/>
''nrdD''
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!{{table_heading_style}} |Product(s)  
!align=left {{table_heading_style}} |Gene Synonym(s)
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[[nrdD:Gene_Product(s)|NrdD product]]<ref name='LIB:Riley_2006'/>: anaerobic ribonucleoside-triphosphate reductase product, B4238 product
''ECK4233, b4238, JW4197''<ref name='LIB:Riley_2006'/>, JW4197''
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!{{table_heading_style}} |Description
!align=left {{table_heading_style}} |Product Desc.
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ribonucleoside-triphosphate reductase<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>  
ribonucleoside-triphosphate reductase<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;


Component of [[:Category:Complex:ribonucleoside-triphosphate reductase|ribonucleoside-triphosphate reductase]]<ref name='LIB:EcoCyc10.6'/>,[[:Category:Complex:anaerobic nucleoside-triphosphate reductase activating system|anaerobic nucleoside-triphosphate reductase activating system]]<ref name='LIB:EcoCyc10.6'/>
Component of [[:Category:Complex:ribonucleoside-triphosphate reductase|ribonucleoside-triphosphate reductase]]<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>; [[:Category:Complex:anaerobic nucleoside-triphosphate reductase activating system|anaerobic nucleoside-triphosphate reductase activating system]]<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>


Ribonucleoside triphosphate reductase, class III, anaerobic<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Product Synonyms(s)
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''anaerobic ribonucleoside-triphosphate reductase<ref name='LIB:Riley_2006'/>, B4238<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, NrdD<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK4233, JW4197, b4238''
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!align=left {{table_heading_style}} |Function from GO
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<GO_nr />
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!{{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!{{table_heading_style}} |Regulation/Expression
!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:nrdDG|nrdDG]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:nrdDG|nrdDG]]<ref name='LIB:EcoCyc10.6'/>  
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!{{table_heading_style}} |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=nrdD&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG11417]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120001382&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=nrdD&loc=MG1655%3A4460683..4458545,W3110%3A4467340..4465202,REL606%3A4445937..4443799,DH10B%3A4562491..4560353,BW2952%3A4397280..4399418]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=4397280&end=4399418&gene=nrdD&aa=mtphvmkrdgckvpfkserikeailraakaaevddadycatvaavvseqmqgrnqvdineiqtavenqlmsgpykqlarayieyrhdrdierekrgrlnqeirglveqtnasllnenankdskviptqrdllagivakhyarqhllprdvvqahergdihyhdldyspffpmfncmlidlkgmltqgfkmgnaeieppksistatavtaqiiaqvashiyggttinridevlapfvtasynkhrktaeewnipdaegyansrtikecydafqsleyevntlhtangqtpfvtfgfglgtswesrliqesilrnriaglgknrktavfpklvfairdglnhkkgdpnydikqlalecaskrmypdilnydqvvkvtgsfktpmgcrsflgvwenengeqihdgrnnlgvislnlprialeakgdeatfwkllderlvlarkalmtriarlegvkarvapilymegacgvrlnadddvseifkngrasislgyigihetinalfggehvydneqlrakgiaiverlrqavdqwkeetgygfslystpsenlcdrfcrldtaefgvvpgvtdkgyytnsfhldvekkvnpydkidfeapypplanggficygeypniqhnlkaledvwdysyqhvpyygtntpidecyecgftgefectskgftcpkcgnhdasrvsvtrrvcgylgspdarpfnagkqeevkrrvkhlgngqig]]&nbsp;&nbsp;  [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=nrdD+AND+escherichia+coli]]&nbsp;&nbsp;  [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=nrdD]]&nbsp;&nbsp;
 
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==Notes==
===Notes===
{{BacktoTop}}
 
Activated NrdD is predicted to be cleaved by oxygen at the Gly681 radical, dropping the last 31 aa.  Requires AdoMet for oxidation of the iron-sulfur center and glycine radical formation. FNR regulon. Binds TrxA (Kumar, 2004).<ref name='LIB:EcoGene'/>
 




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==References==
==References==
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Latest revision as of 21:47, 27 May 2013

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Standard Name

nrdD

Gene Synonym(s)

ECK4233, b4238, JW4197[1], JW4197

Product Desc.

ribonucleoside-triphosphate reductase[2][3];

Component of ribonucleoside-triphosphate reductase[2][3]; anaerobic nucleoside-triphosphate reductase activating system[2][3]

Ribonucleoside triphosphate reductase, class III, anaerobic[4]

Product Synonyms(s)

anaerobic ribonucleoside-triphosphate reductase[1], B4238[2][1], NrdD[2][1] , ECK4233, JW4197, b4238

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): nrdDG[2]

Regulation/Activity
Quick Links



        

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Notes

[back to top]


Activated NrdD is predicted to be cleaved by oxygen at the Gly681 radical, dropping the last 31 aa. Requires AdoMet for oxidation of the iron-sulfur center and glycine radical formation. FNR regulon. Binds TrxA (Kumar, 2004).[4]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 3.2 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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