PMID:16859555: Difference between revisions
New PMID: Page! |
imported>Wikientrybot change PMID template to TableEdit version |
||
| (3 intermediate revisions by 2 users not shown) | |||
| Line 1: | Line 1: | ||
{{RightTOC}} | |||
<!--box uid=d41d8cd98f00b204e9800998ecf8427e.180641.O52238d42450f9--> | |||
<!-- | |||
****************************************************************************************** | |||
* | |||
* ** PLEASE DON'T EDIT THIS TABLE DIRECTLY. Use the edit table link under the table. ** | |||
* | |||
****************************************************************************************** --> | |||
{| id="O52238d42450f9" class=" tableEdit PMID_info_table" | |||
|- | |||
!align=left |Citation | |||
|| | |||
'''Collins, SR, Schuldiner, M, Krogan, NJ and Weissman, JS''' (2006) A strategy for extracting and analyzing large-scale quantitative epistatic interaction data. ''Genome Biol.'' '''7''':R63 | |||
|- | |||
!align=left |Abstract | |||
|| | |||
Recently, approaches have been developed for high-throughput identification of synthetic sick/lethal gene pairs. However, these are only a specific example of the broader phenomenon of epistasis, wherein the presence of one mutation modulates the phenotype of another. We present analysis techniques for generating high-confidence quantitative epistasis scores from measurements made using synthetic genetic array and epistatic miniarray profile (E-MAP) technology, as well as several tools for higher-level analysis of the resulting data that are greatly enhanced by the quantitative score and detection of alleviating interactions. | |||
|- | |||
!align=left |Links | |||
|| | |||
[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16859555 PubMed] [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1779568 PMC1779568] | |||
Online version:[http://dx.doi.org/10.1186/gb-2006-7-7-r63 10.1186/gb-2006-7-7-r63] | |||
|- | |||
!align=left |Keywords | |||
|| | |||
Epistasis, Genetic; Mutation; Oligonucleotide Array Sequence Analysis; Phenotype | |||
|- class="tableEdit_footer" | |||
|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=d41d8cd98f00b204e9800998ecf8427e.180641.O52238d42450f9&page=180641&pagename={{FULLPAGENAMEE}}&type=1&template=PMID_info_table edit table]</span> || | |||
|} | |||
<!--box uid=d41d8cd98f00b204e9800998ecf8427e.180641.O52238d42450f9--> | |||
==Significance {{HelpIcon|Help:Literature}} == | |||
{{LitSignificance}} | |||
== Useful Materials and Methods {{HelpIcon|Help:Literature}}== | |||
{{LitMaterials}} | |||
==Annotations {{HelpIcon|Help:Literature}}== | |||
<protect><annotationlinks/></protect> | |||
==EcoliWiki Links {{HelpIcon|Help:Literature}} == | |||
{{LitLinks}} | |||
==See also== | |||
==References== | |||
{{RefHelp}} | |||
<references/> | |||
Latest revision as of 04:30, 15 September 2013
| Citation |
Collins, SR, Schuldiner, M, Krogan, NJ and Weissman, JS (2006) A strategy for extracting and analyzing large-scale quantitative epistatic interaction data. Genome Biol. 7:R63 |
|---|---|
| Abstract |
Recently, approaches have been developed for high-throughput identification of synthetic sick/lethal gene pairs. However, these are only a specific example of the broader phenomenon of epistasis, wherein the presence of one mutation modulates the phenotype of another. We present analysis techniques for generating high-confidence quantitative epistasis scores from measurements made using synthetic genetic array and epistatic miniarray profile (E-MAP) technology, as well as several tools for higher-level analysis of the resulting data that are greatly enhanced by the quantitative score and detection of alleviating interactions. |
| Links |
PubMed PMC1779568 Online version:10.1186/gb-2006-7-7-r63 |
| Keywords |
Epistasis, Genetic; Mutation; Oligonucleotide Array Sequence Analysis; Phenotype |
| edit table |
Significance
You can help EcoliWiki by summarizing why this paper is useful
Useful Materials and Methods
You can help Ecoliwiki by describing the useful materials (strains, plasmids, antibodies, etc) described in this paper.
Annotations
<annotationlinks/>
EcoliWiki Links
Add links to pages that link here (e.g. gene, product, method pages)
See also
References
See Help:References for how to manage references in EcoliWiki.