bioB:Quickview: Difference between revisions

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!{{table_heading_style}} |Gene Name
!align=left {{table_heading_style}} |Standard Name
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[[bioB:Gene|''bioB]]'' (synonyms: ''ECK0764, b0775, JW0758, G8004'')<ref name='LIB:Riley_2006'/><ref name='LIB:EcoCyc10.6'/>
''bioB''
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!{{table_heading_style}} |Product(s)  
!align=left {{table_heading_style}} |Gene Synonym(s)
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[[bioB:Gene_Product(s)|BioB product]]<ref name='LIB:Riley_2006'/>: biotin synthase product, B0775 product
''ECK0764, b0775, JW0758, G8004''<ref name='LIB:Riley_2006'/><ref name='LIB:EcoCyc10.6'/>
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!{{table_heading_style}} |Description
!align=left {{table_heading_style}} |Product Desc.
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biotin synthase monomer<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>  
biotin synthase<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;


Component of [[:Category:Complex:biotin synthase|biotin synthase]]<ref name='LIB:EcoCyc10.6'/>
Component of [[:Category:Complex:biotin synthase|biotin synthase]]<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>


Biotin synthase; dethiobiotin to biotin pathway; iron-sulfur enzyme<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Product Synonyms(s)
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''biotin synthase<ref name='LIB:Riley_2006'/>, B0775<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, BioB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK0764, JW0758, b0775''
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!align=left {{table_heading_style}} |Function from GO
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<GO_nr />
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!{{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!{{table_heading_style}} |Regulation/Expression
!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:bioBFCD|bioBFCD]]<ref name='LIB:EcoCyc10.6'/>, OP00157  
transcription unit(s): [[:Category:Txn_unit:bioBFCD|bioBFCD]]<ref name='LIB:EcoCyc10.6'/>, OP00157  
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!{{table_heading_style}} |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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!align=left {{table_heading_style}} |Quick Links
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[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=bioB&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG10118]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120000114&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=bioB&loc=MG1655%3A808567..809607,W3110%3A809766..810806,DH10B%3A862495..863535,REL606%3A801970..803010,BW2952%3A711535..712575]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=711535&end=712575&gene=bioB&aa=mahrprwtlsqvtelfekplldllfeaqqvhrqhfdprqvqvstllsiktgacpedckycpqssryktgleaerlmeveqvlesarkakaagstrfcmgaawknpherdmpyleqmvqgvkamgleacmtlgtlsesqaqrlanagldyynhnldtspefygniittrtyqerldtlekvrdagikvcsggivglgetvkdraglllqlanlptppesvpinmlvkvkgtpladnddvdafdfirtiavarimmptsyvrlsagreqmneqtqamcfmagansifygckllttpnpeedkdlqlfrklglnpqqtavlagdneqqqrleqalmtpdtdeyynaaal]]&nbsp;&nbsp;  [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=bioB+AND+escherichia+coli]]&nbsp;&nbsp;  [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=bioB]]&nbsp;&nbsp;
 
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===Notes===
===Notes===
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Radical SAM superfamily.  BioB contains two distinct Fe-S cluster binding sites, one site accommodates a [2Fe-2S](2+) cluster with partial noncysteinyl ligation, the other site accommodates a [4Fe-4S](2+,+) cluster that binds S-adenosylmethionine (SAM) at a unique Fe site of the [4Fe-4S](2+) cluster and undergoes O(2)-induced degradation via a distinct type of [2Fe-2S](2+) cluster intermediate.<ref name='LIB:EcoGene'/>




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==References==
==References==
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Latest revision as of 21:52, 27 May 2013

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Standard Name

bioB

Gene Synonym(s)

ECK0764, b0775, JW0758, G8004[1][2]

Product Desc.

biotin synthase[2][3];

Component of biotin synthase[2][3]

Biotin synthase; dethiobiotin to biotin pathway; iron-sulfur enzyme[4]

Product Synonyms(s)

biotin synthase[1], B0775[2][1], BioB[2][1] , ECK0764, JW0758, b0775

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): bioBFCD[2], OP00157

Regulation/Activity
Quick Links



        

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Notes

[back to top]


Radical SAM superfamily. BioB contains two distinct Fe-S cluster binding sites, one site accommodates a [2Fe-2S](2+) cluster with partial noncysteinyl ligation, the other site accommodates a [4Fe-4S](2+,+) cluster that binds S-adenosylmethionine (SAM) at a unique Fe site of the [4Fe-4S](2+) cluster and undergoes O(2)-induced degradation via a distinct type of [2Fe-2S](2+) cluster intermediate.[4]



References

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  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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