chbR:Quickview: Difference between revisions

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!{{table_heading_style}} |Gene Name
!align=left {{table_heading_style}} |Standard Name
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[[chbR:Gene|''chbR]]'' (synonyms: ''ECK1733, b1735, JW1724, celD'')<ref name='LIB:Riley_2006'/>
''chbR''
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!{{table_heading_style}} |Product(s)  
!align=left {{table_heading_style}} |Gene Synonym(s)
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[[chbR:Gene_Product(s)|ChbR product]]<ref name='LIB:Riley_2006'/>: DNA-binding transcriptional dual regulator product, B1735 product, CelD product
''ECK1733, b1735, JW1724, celD''<ref name='LIB:Riley_2006'/>, celD''
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!{{table_heading_style}} |Description
!align=left {{table_heading_style}} |Product Desc.
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ChbR transcriptional regulator<ref name='LIB:EcoCyc10.6'/> ChbR transcriptional dual regulator<ref name='LIB:EcoCyc11.1'/>  
ChbR transcriptional regulator<ref name='LIB:EcoCyc10.6'/>; ChbR transcriptional dual regulator<ref name='LIB:EcoCyc11.1'/>


Repressor, chb operon for N,N'-diacetylchitobiose utilization; AraC family <ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Product Synonyms(s)
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''DNA-binding transcriptional dual regulator<ref name='LIB:Riley_2006'/>, B1735<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, ChbR<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, CelD<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , celD, ECK1733, JW1724, b1735''
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!align=left {{table_heading_style}} |Function from GO
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<GO_nr />
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!{{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Knock-Out Phenotype
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Chitobiose negative and Cellobiose negative
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!{{table_heading_style}} |Regulation/Expression
!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:chbBCARFG|chbBCARFG]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:chbBCARFG|chbBCARFG]]<ref name='LIB:EcoCyc10.6'/>  
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!{{table_heading_style}} |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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Repressor in the absence of inducer and activator in the presence of inducer.
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!align=left {{table_heading_style}} |Quick Links
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[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=chbR&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG10143]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120000139&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=chbR&loc=MG1655%3A1817471..1816629,W3110%3A1821161..1820319,DH10B%3A1908042..1907200,REL606%3A1795870..1796712,BW2952%3A1708688..1709530]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=1708688&end=1709530&gene=chbR&aa=mmqpvinapeiatareqqlfngknfhvfiynktesisglhqhdyyeftlvltgryfqeingkrvllergdfvfiplgshhqsfyefgatrilnvgiskrffeqhylpllpycfvasqvyrtnnafltyvetvisslnfretgleefvemvtfyvinrlrhyreeqviddvpqwlkstvekmhdkeqfsesalenmvalsaksqeyltratqryygktpmqiineirinfakkqlemtnysvtdiafeagysspslfiktfkkltsftpksyrkkltefnq]]&nbsp;&nbsp;  [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=chbR+AND+escherichia+coli]]&nbsp;&nbsp;  [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=chbR]]&nbsp;&nbsp;


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ChbR was initially reported as a repressor of the ''chb'' operon. However later work showed that this protein is an activator as well as the repressor of the ''chb'' operon. The mutations in the ''chbR'' have also been reported to confer Cel<sup>+</sup> phenotype to ''E. coli''.
==References==
==References==
<ref name='PMID:18028317'/>
<ref name='PMID:15066032'/>
<ref name='PMID:9405618'/>
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Latest revision as of 21:52, 27 May 2013

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Standard Name

chbR

Gene Synonym(s)

ECK1733, b1735, JW1724, celD[1], celD

Product Desc.

ChbR transcriptional regulator[2]; ChbR transcriptional dual regulator[3]

Repressor, chb operon for N,N'-diacetylchitobiose utilization; AraC family [4]

Product Synonyms(s)

DNA-binding transcriptional dual regulator[1], B1735[2][1], ChbR[2][1], CelD[2][1] , celD, ECK1733, JW1724, b1735

Function from GO

<GO_nr />

Knock-Out Phenotype

Chitobiose negative and Cellobiose negative

Regulation/Expression

transcription unit(s): chbBCARFG[2]

Regulation/Activity

Repressor in the absence of inducer and activator in the presence of inducer.

Quick Links



        

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Notes

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ChbR was initially reported as a repressor of the chb operon. However later work showed that this protein is an activator as well as the repressor of the chb operon. The mutations in the chbR have also been reported to confer Cel+ phenotype to E. coli.

References

[5] [6] [7]

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ Kachroo, AH et al. (2007) Mutations that alter the regulation of the chb operon of Escherichia coli allow utilization of cellobiose. Mol. Microbiol. 66 1382-95 PubMed
  6. ↑ Plumbridge, J & Pellegrini, O (2004) Expression of the chitobiose operon of Escherichia coli is regulated by three transcription factors: NagC, ChbR and CAP. Mol. Microbiol. 52 437-49 PubMed
  7. ↑ Keyhani, NO & Roseman, S (1997) Wild-type Escherichia coli grows on the chitin disaccharide, N,N'-diacetylchitobiose, by expressing the cel operon. Proc. Natl. Acad. Sci. U.S.A. 94 14367-71 PubMed
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