hha:Quickview: Difference between revisions

From EcoliWiki
Jump to navigation Jump to search
← Older edit
imported>WikiEntryBot
Automated import of articles
touch
 
(18 intermediate revisions by 4 users not shown)
Line 1: Line 1:
<!--PLEASE EDIT FROM THE SECTION OR TABLE EDIT LINKS...IF YOU SEE THIS MESSAGE, YOU'RE PROBABLY IN THE WRONG PLACE-->
<!--
***************************************************************************************************************************************************
*
*
*              PLEASE EDIT FROM THE SECTION OR TABLE EDIT LINKS...IF YOU SEE THIS MESSAGE,
*                            YOU'RE PROBABLY IN THE WRONG PLACE
*
*
***************************************************************************************************************************************************
-->{{#css:Suppresslinks.css}}<css>{{:Suppresslinks.css}}</css>
<noinclude>{{TabsTop}}   
<noinclude>{{TabsTop}}   
{{Tab On|Quickview|hha}}{{Tab|Gene|hha}}{{Tab|Gene Product(s)|hha}}{{Tab|Expression|hha}}{{Tab|Evolution|hha}}{{Tab|On One Page|hha}}{{TabsBottom}}
{{Tab On|Quickview|hha}}{{Tab|Gene|hha}}{{Tab|Gene Product(s)|hha}}{{Tab|Expression|hha}}{{Tab|Evolution|hha}}{{Tab|On One Page|hha}}{{TabsBottom}}
Line 8: Line 17:
|}
|}
</noinclude>
</noinclude>
<!--box uid=421aa90e079fa326b6494f812ad13e79..U469f8fe3d75a1-->
<protect><!--box uid=bc145ea147f7e36caf09c1bfeed4ee9d.2671.R49aee8ba71c8a-->
<!--*** PLEASE DON'T EDIT THIS TABLE DIRECTLY.  Use the edit table link under the table. *** -->
<!--
{|{{Prettytable}}
******************************************************************************************
*
*  ** PLEASE DON'T EDIT THIS TABLE DIRECTLY.  Use the edit table link under the table. **
*
****************************************************************************************** -->
{|   id="R49aee8ba71c8a"  class=" tableEdit New_Quickview_Table" 
 
|-
|-
!{{table_heading_style}} |Gene Name
!align=left {{table_heading_style}} |Standard Name
|
||
[[hha:Gene|''hha]]'' (synonyms: ''ECK0454, b0460, JW0449'')<ref name='LIB:Riley_2006'/>
''hha''
|-
|-
!{{table_heading_style}} |Product(s)  
!align=left {{table_heading_style}} |Gene Synonym(s)
|
||
[[hha:Gene_Product(s)|Hha product]]<ref name='LIB:Riley_2006'/>: modulator of gene expression, with H-NS product, B0460 product
''ECK0454, b0460, JW0449''<ref name='LIB:Riley_2006'/>, JW0449''
|-
|-
!{{table_heading_style}} |Description
!align=left {{table_heading_style}} |Product Desc.
|
||
haemolysin expression modulating protein<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>  
haemolysin expression modulating protein<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
 
Modulates hemolysin expression, in complex with H-NS; stimulates transposition events; induced by AI-2 pheromone; promotes conjugation and conjugation-induced biofilms<ref name='LIB:EcoGene'/>


Hha is a small transcriptional regulator (8 kDa) that is induced in biofilms<ref name='PMID:14727089'/> and that influences biofilm formation<ref name='PMID:16317765'/>; Hha overexpression reduces biofilm formation by increasing biofilm dispersal<ref name='PMID:18545668'/>.  Rather than binding to specific DNA sequences, Hha exhibits non-specific DNA binding.  Hha binds in vivo to 15 genes or intergenic regions of CP4-57 and DLP12 including regions close to the prophage attachment (att) sites and that Hha activates the prophage lytic genes ''alpA'', ''rzpD'', ''appY'' and ''yfjZ'', as well as induces plaque formation and decreases cell viability<ref name='PMID:18545668'/>.
|-
!align=left {{table_heading_style}} |Product Synonyms(s)
||
''modulator of gene expression, with H-NS<ref name='LIB:Riley_2006'/>, B0460<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Hha<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK0454, JW0449, b0460''
|-
!align=left {{table_heading_style}} |Function from GO
||
<GO_nr />
|-
|-
!{{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Knock-Out Phenotype
|
||


|-
|-
!{{table_heading_style}} |Regulation/Expression
!align=left {{table_heading_style}} |Regulation/Expression
|
||
transcription unit(s): [[:Category:Txn_unit:hha|hha]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:hha|hha]]<ref name='LIB:EcoCyc10.6'/>  
|-
|-
!{{table_heading_style}} |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
|
||


|-
|-
|colspan='2'|[{{SERVER}}/colipedia/index.php/Special:TableEdit?id=421aa90e079fa326b6494f812ad13e79..U469f8fe3d75a1&page=&pagename={{FULLPAGENAMEE}} edit table]
!align=left {{table_heading_style}} |Quick Links
||
[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=hha&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG10439]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120000432&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=hha&loc=MG1655%3A479532..479314,W3110%3A479532..479314,DH10B%3A418863..418645,REL606%3A452375..452157,BW2952%3A382073..382291]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=382073&end=382291&gene=hha&aa=msekpltktdylmrlrrcqtidtlervieknkyelsdnelavfysaadhrlaeltmnklydkipssvwkfir]]&nbsp;&nbsp;  [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=hha+AND+escherichia+coli]]&nbsp;&nbsp;  [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=hha]]&nbsp;&nbsp;
 
|- class="tableEdit_footer"
|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=bc145ea147f7e36caf09c1bfeed4ee9d.2671.R49aee8ba71c8a&page=2671&pagename={{FULLPAGENAMEE}}&type=1&template=New_Quickview_Table edit table]</span> ||
|}
|}
<!--box uid=421aa90e079fa326b6494f812ad13e79..U469f8fe3d75a1-->
<!--box uid=bc145ea147f7e36caf09c1bfeed4ee9d.2671.R49aee8ba71c8a--></protect>
{{Quickview_table_help}}
<protect><!--Quickview_notes--></protect>
<protect><!--Quickview_notes--></protect>
==Notes==
===Notes===
{{BacktoTop}}
 
Hha and Cnu are paralogs. The expression of the hly operon of plasmid pHly152 is modulatedby Hha/HN-S. Overexpression of Cnu(YdgT) partially suppresses the hha defect on hylA expression. Hha positively modulates H-NS expression. Induced during biofilm formation.<ref name='LIB:EcoGene'/>
 




<noinclude>
<noinclude>
==References==
==References==
{{BacktoTop}}
<references/>
<references/>
</noinclude>
</noinclude>

Latest revision as of 21:49, 27 May 2013

{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Standard Name

hha

Gene Synonym(s)

ECK0454, b0460, JW0449[1], JW0449

Product Desc.

haemolysin expression modulating protein[2][3]

Modulates hemolysin expression, in complex with H-NS; stimulates transposition events; induced by AI-2 pheromone; promotes conjugation and conjugation-induced biofilms[4]

Hha is a small transcriptional regulator (8 kDa) that is induced in biofilms[5] and that influences biofilm formation[6]; Hha overexpression reduces biofilm formation by increasing biofilm dispersal[7]. Rather than binding to specific DNA sequences, Hha exhibits non-specific DNA binding. Hha binds in vivo to 15 genes or intergenic regions of CP4-57 and DLP12 including regions close to the prophage attachment (att) sites and that Hha activates the prophage lytic genes alpA, rzpD, appY and yfjZ, as well as induces plaque formation and decreases cell viability[7].

Product Synonyms(s)

modulator of gene expression, with H-NS[1], B0460[2][1], Hha[2][1] , ECK0454, JW0449, b0460

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): hha[2]

Regulation/Activity
Quick Links



        

edit table

See Help:Quickview for help with entering information in the Quickview table.

Notes

[back to top]


Hha and Cnu are paralogs. The expression of the hly operon of plasmid pHly152 is modulatedby Hha/HN-S. Overexpression of Cnu(YdgT) partially suppresses the hha defect on hylA expression. Hha positively modulates H-NS expression. Induced during biofilm formation.[4]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ Ren, D et al. (2004) Gene expression in Escherichia coli biofilms. Appl. Microbiol. Biotechnol. 64 515-24 PubMed
  6. ↑ Barrios, AF et al. (2006) Hha, YbaJ, and OmpA regulate Escherichia coli K12 biofilm formation and conjugation plasmids abolish motility. Biotechnol. Bioeng. 93 188-200 PubMed
  7. ↑ 7.0 7.1 García-Contreras, R et al. (2008) Protein translation and cell death: the role of rare tRNAs in biofilm formation and in activating dormant phage killer genes. PLoS ONE 3 e2394 PubMed
Retrieved from "https://ecoliwiki.org/colipedia/index.php?title=hha:Quickview&oldid=1396852"