htpX:Quickview: Difference between revisions
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!align=left {{table_heading_style}} |Gene Synonym(s) | !align=left {{table_heading_style}} |Gene Synonym(s) | ||
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''ECK1828, b1829, JW1818''<ref name='LIB:Riley_2006'/> | ''ECK1828, b1829, JW1818''<ref name='LIB:Riley_2006'/>, JW1818'' | ||
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!align=left {{table_heading_style}} |Product Desc. | !align=left {{table_heading_style}} |Product Desc. | ||
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!align=left {{table_heading_style}} |Product Synonyms(s) | !align=left {{table_heading_style}} |Product Synonyms(s) | ||
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predicted endopeptidase<ref name='LIB:Riley_2006'/>, B1829<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, HtpX<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> | ''predicted endopeptidase<ref name='LIB:Riley_2006'/>, B1829<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, HtpX<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK1828, JW1818, b1829'' | ||
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!align=left {{table_heading_style}} |Function from GO | !align=left {{table_heading_style}} |Function from GO | ||
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!align=left {{table_heading_style}} |Quick Links | !align=left {{table_heading_style}} |Quick Links | ||
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[http://porteco.org/AjaxSearch.jsp?searchString=htpX&s=search | [[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=htpX&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG10462]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120000455&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=htpX&loc=MG1655%3A1910600..1909719,W3110%3A1914290..1913409,DH10B%3A2001171..2000290,REL606%3A1891153..1890272,BW2952%3A1801778..1802659]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=1801778&end=1802659&gene=htpX&aa=mmrialflltnlavmvvfglvlsltgiqsssvqglmimallfgfggsfvsllmskwmalrsvggevieqprnererwlvntvatqarqagiampqvaiyhapdinafatgarrdaslvavstgllqnmspdeaeaviaheishiangdmvtmtliqgvvntfvifisrilaqlaagfmggnrdegeesngnpliyfavatvlelvfgilasiitmwfsrhrefhadagsaklvgrekmiaalqrlktsyepqeatsmmalcingkskslselfmthppldkriealrtgeylk]] [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=htpX+AND+escherichia+coli]] [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=htpX]] | ||
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Latest revision as of 21:49, 27 May 2013
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
| Standard Name |
htpX |
|---|---|
| Gene Synonym(s) |
ECK1828, b1829, JW1818[1], JW1818 |
| Product Desc. |
heat shock protein, integral membrane protein[2][3] Zinc metalloprotease HtpX, membrane-bound; cleaves SecY in vivo and in vitro; self-cleaves; M48 family[4] |
| Product Synonyms(s) |
predicted endopeptidase[1], B1829[2][1], HtpX[2][1] , ECK1828, JW1818, b1829 |
| Function from GO |
<GO_nr /> |
| Knock-Out Phenotype | |
| Regulation/Expression | |
| Regulation/Activity | |
| Quick Links |
|
| edit table |
See Help:Quickview for help with entering information in the Quickview table.
Notes
Overexpression of truncated HtpX promotes degradation of incomplete proteins in puromycin-treated cells. HtpX collaborates with FtsH to eliminate abnormal membrane proteins: an hflX ftsH double mutant is temperature-sensitive for growth. Inactivation of putative protease active site residues abolishes ability to cross-complement defects in the FtsH protease. Start codon verified by toeprint analysis (Kornitzer, 1991). HtpX has a cytosolic active site. HtpX in vivo cleavage of SecY is seen when both are overproduced. Cpx regulon. RpoH regulon. Synthetic lethal with hflB(ftsH) in fabZ(SfhC) background. HtpX has two TM helices. htpX, yggG, yfgC and ycaL are paralogs.[4]
References
- ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.