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{{Tab On|Quickview|mdtE}}{{Tab|Gene|mdtE}}{{Tab|Gene Product(s)|mdtE}}{{Tab|Expression|mdtE}}{{Tab|Evolution|mdtE}}{{Tab|On One Page|mdtE}}{{TabsBottom}}
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!{{table_heading_style}} |Gene Name
!align=left {{table_heading_style}} |Standard Name
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[[mdtE:Gene|''mdtE]]'' (synonyms: ''ECK3497, b3513, JW3481, yhiU'')<ref name='LIB:Riley_2006'/>
''mdtE''
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!{{table_heading_style}} |Product(s)  
!align=left {{table_heading_style}} |Gene Synonym(s)
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[[mdtE:Gene_Product(s)|MdtE product]]<ref name='LIB:Riley_2006'/>: multidrug resistance efflux transporter<ref name='LIB:Riley_2006'/>, MdtE<ref name='LIB:EcoCyc10.6'/>, B3513<ref name='LIB:EcoCyc10.6'/>, YhiU<ref name='LIB:EcoCyc10.6'/>, [[:Category:Complex:MdtEF multidrug transporter|MdtEF multidrug transporter]]<ref name='LIB:EcoCyc10.6'/>
''ECK3497, b3513, JW3481, yhiU''<ref name='LIB:Riley_2006'/>, yhiU''
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!{{table_heading_style}} |Description
!align=left {{table_heading_style}} |Product Desc.
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MdtE<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
MdtE<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;


Component of [[:Category:Complex:MdtEF multidrug transporter|MdtEF multidrug transporter]]<ref name='LIB:EcoCyc10.6'/>; [[:Category:Complex:MdtEF multidrug transporter|MdtEF-Tolc Multidrug Efflux Transport System]]<ref name='LIB:EcoCyc11.1'/>


MdtEF-TolC multidrug resistance efflux transporter; membrane fusion protein (MFP) component, lipoprotein; overexpression resistance to erythromycin, deoxycholate, octane and rhodamine; no mutant phenotype<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Product Synonyms(s)
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''multidrug resistance efflux transporter<ref name='LIB:Riley_2006'/>, MdtE<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, B3513<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YhiU<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK3497, JW3481, yhiU, b3513''
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!align=left {{table_heading_style}} |Function from GO
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<GO_nr />
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!{{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!{{table_heading_style}} |Regulation/Expression
!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:txn_units:mdtE|mdtE]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:mdtE|mdtE]]<ref name='LIB:EcoCyc10.6'/>  
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!{{table_heading_style}} |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=mdtE&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG12240]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120002123&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=mdtE&loc=MG1655%3A3657255..3658412,W3110%3A3981183..3980026,DH10B%3A3755000..3756157,BW2952%3A3545749..3546906]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=3545749&end=3546906&gene=mdtE&aa=mnrrrkllipllfcgamltacddksaenaaamtpevgvvtlspgsvnvlselpgrtvpyevaeirpqvggiiikrnfiegdkvnqgdslyqidpaplqaelnsakgslakalstasnaritfnrqasllktnyvsrqdydtartqlneaeanvtvakaaveqatinlqyanvtspitgvsgkssvtvgalvtanqadslvtvqrldpiyvdltqsvqdflrmkeevasgqikqvqgstpvqlnlengkrysqtgtlkfsdptvdettgsvtlraifpnpngdllpgmyvtalvdegsrqnvllvpqegvthnaqgkatalildkddvvqlreieaskaigdqwvvtsglqagdrvivsglqrirpgikaraisssqenasteskq]]&nbsp;&nbsp;  [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=mdtE+AND+escherichia+coli]]&nbsp;&nbsp;  [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=mdtE]]&nbsp;&nbsp;
 
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==Notes==
===Notes===
{{BacktoTop}}
 
EvgAS regulon. First 20 aa are a type II signal peptide. N-acetyl-D-glucosamine inducible, via Crp (Hirakawa, 2006). Crp represses mdtEF (Nishino, 2008).<ref name='LIB:EcoGene'/>
 




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==References==
==References==
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<references/>
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Latest revision as of 21:48, 27 May 2013

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Standard Name

mdtE

Gene Synonym(s)

ECK3497, b3513, JW3481, yhiU[1], yhiU

Product Desc.

MdtE[2][3];

Component of MdtEF multidrug transporter[2]; MdtEF-Tolc Multidrug Efflux Transport System[3]

MdtEF-TolC multidrug resistance efflux transporter; membrane fusion protein (MFP) component, lipoprotein; overexpression resistance to erythromycin, deoxycholate, octane and rhodamine; no mutant phenotype[4]

Product Synonyms(s)

multidrug resistance efflux transporter[1], MdtE[2][1], B3513[2][1], YhiU[2][1] , ECK3497, JW3481, yhiU, b3513

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): mdtE[2]

Regulation/Activity
Quick Links



        

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Notes

[back to top]


EvgAS regulon. First 20 aa are a type II signal peptide. N-acetyl-D-glucosamine inducible, via Crp (Hirakawa, 2006). Crp represses mdtEF (Nishino, 2008).[4]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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