View source for Phage T7

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Bacteriophage T7 is a virulent phage with an icosahedral head, a short noncontractile tail, and a dsDNA genome of 39937 bp.  
== Phage structure ==

== Genome structure ==

Between 387400 and 40000 bases in a single, linear molecule of dsDNA

Gene 1: specifies RNA polymerase; Genes 2-6: affect kinetics of DNA synthesis; Genes 7-17: specify proteins found within partially and fully assembled particles; Genes 18-19: involved in the maturation of the DNA

== Life Cycle ==
=== Host recognition ===

Lipopolysaccharides on the external cell wall of the host cell provide recognition for the Phage

=== DNA entry ===

A protrusion of the Phage (sometimes called a Tail) lengthens and attaches the Phage to the Host cell, and proceeds to send the virus' dsDNA through the channel. After the first 850 to 1000 base pairs, the insertion is paused until an injection promoter allows it to continue.

=== Early gene expression ===

=== DNA replication ===

=== Late transcription ===

=== Packaging ===

=== Lysis ===

== See also ==
* [[:Category:Gene_List:Phage_T7|Links to T7 gene pages in EcoliWiki]]
* Studier <ref name='PMID:4554613'/> wrote an overview of t7 biology in genetics in 1972.
* Krüger DH and Schroeder C (1981)<ref name='PMID:6261110'/>

== References ==
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