nepI:Quickview

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

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Standard Name

nepI

Gene Synonym(s)

yicM, ECK3653, b3662, JW5938[1][2], gaiA, JW5938

Product Desc.

NepI MFS ribonucleoside transporter[2][3]

Purine ribonucleoside exporter; 6-mercaptopurine resistance[4]

Product Synonyms(s)

predicted transporter[1], B3662[2][1], YicM[2][1], NepI[2][1] , ECK3653, gaiA, JW5938, yicM, b3662

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): yicM[2]

Regulation/Activity
Quick Links

porteco.png EcoCyc.gif regulondb.jpg

dnadisplay.png proteindisplay.png   pubmed.jpg   textpresso.jpg  

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Notes

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Overexpression of nepI increases resistance to inosine and guanosine. Salmonella gaiA(nepI) is required for triggering apoptosis and bacterial survival in murine macrophages. Pathogenicity island eip (EAEC strain 042) has inserted in the yicS-nepI intergenic region. Major Facilitator Superfamily (MFS).[4]



References

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  1. 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.