hpf:Quickview

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
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Standard Name

hpf

Gene Synonym(s)

yhbH, ECK3192, b3203, JW3170, rp5M[1][2]

Product Desc.

probable sigma-54 modulation protein[3]; predicted ribosome-associated, sigma 54 modulation protein[2]

Ribosome hibernation promoting factor HPF; stabilizes 70S dimers (100S); induced in stationary phase; raiA paralog has opposite effect on 70S dimers[4]

Product Synonyms(s)

predicted ribosome-associated, sigma 54 modulation protein[1], B3203[3][1], YhbH[3][1], Hpf[2][1] , ECK3192, JW3170, yhbH, b3203

Function from GO

<GO_nr />

Knock-Out Phenotype

Non-essential [5]

Regulation/Expression

transcription unit(s): lptB-rpoN-yhbH-ptsN-yhbJ[3], yhbG-rpoN-yhbH-ptsN-yhbJ, rpoN-yhbH-ptsN-yhbJ-npr[3], rpoN-ORFII-ORF-III-ORF-IV-ORFV, rpoN-yhbH-ptsN-yhbJ-ptsO

Regulation/Activity
Quick Links

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Notes

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Homologous to RpoN modulators. Induced by AI-2 pheromone. The rpoN operon contains rpoN-hpf-ptsN-yhbJ-npr.[4]



References

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  1. 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 3.2 3.3 3.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. Bubunenko, M et al. (2007) Essentiality of ribosomal and transcription antitermination proteins analyzed by systematic gene replacement in Escherichia coli. J. Bacteriol. 189 2844-53 PubMed