mug:Quickview
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
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| Standard Name |
mug |
|---|---|
| Gene Synonym(s) | |
| Product Desc. |
stationary phase mismatch/uracil DNA glycosylase[2][3] Uracil DNA-glycosylase, G:U mismatch-specific, dsDNA-specific; excises uracil from DNA by base flipping mechanism; required for mutation avoidance in stationary phase; up-regulated in stationary phase[4] |
| Product Synonyms(s) |
G/U mismatch-specific DNA glycosylase[1], B3068[2][1], YgjF[2][1], Mug[2][1], dsUDG[2][1] , dug, ECK3058, JW3040, ygjF, b3068 |
| Function from GO |
<GO_nr /> |
| Knock-Out Phenotype | |
| Regulation/Expression | |
| Regulation/Activity | |
| Quick Links |
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| edit table |
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Notes
Endonuclease IV stimulates Mug activity in vitro by promoting disassociation from the DNA and enzyme turnover. Mug can also excise a damaged basepair, epsilonC:G, containing 3,N(4)-ethenocytosine. Native Mug has been verified using mass spec by Sung and Mosbaugh: 18670 daltons obs. vs 18673 calc. indicates initial Met is not clipped.[4]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
