uup:Quickview
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
<protect>
| Standard Name |
uup |
|---|---|
| Gene Synonym(s) | |
| Product Desc. |
ATP-binding protein with possible role in replication[2][3] DNA-binding ATPase involved in replication; cytosolic; mutant displays an increased frequency of precise excision of transposons and defective growth of bacteriophage Mu[4] |
| Product Synonyms(s) |
fused predicted transporter subunits of ABC superfamily: ATP-binding components[1], B0949[2][1], YcbH[2][1], YcbI[2][1], Uup[2][1], Tex[2][1] , ECK0940, JW0932, ycbH, ycbI, b0949 |
| Function from GO |
<GO_nr /> |
| Knock-Out Phenotype | |
| Regulation/Expression | |
| Regulation/Activity | |
| Quick Links |
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| edit table |
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Notes
Has two ABC ATPase domains; ATPase activity is essential for function. A C-terminal domain of the protein displays predicted structural homology with the Little Finger domain of Y family DNA polymerases and is involved in DNA binding.[4]
Similar to yeast proteins involved in ribosomal function and assembly.
References
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
