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References Suggestions


Standard Name


Gene Synonym(s)

ECK2739, b2744, JW2714, ygbC[1], ygbC

Product Desc.

broad specificity 5'(3')-nucleotidase and polyphosphatase[2][3]

Nucleotidase, 5- or 3'-monophosphates; purine, pyrimidine, ribo- and deoxyribonucleotides all effectively hydrolyzed; short chain exopolyphosphatase[4]

Product Synonyms(s)

broad specificity 5'(3')-nucleotidase and polyphosphatase[1], B2744[2][1], YgbC[2][1], SurE[2][1] , ECK2739, JW2714, ygbC, b2744

Function from GO

<GO_nr />

Knock-Out Phenotype

transcription unit(s): surE-pcm[2]

Quick Links

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A surE mutation is a specific suppressor of pcm stationary phase survival defects. The original surE mutant had a secondary rpoS mutation. The lack of survival in stationary phase was due to this cryptic rpoS mutation and clean surE mutants have no survival phenotype. SurE demonstrates nucleotidase preference for short chain substrates. otherPDB (T. maritima): 1J9J, 1J9K, 1J9L, 1ILV.[4]


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  1. 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.