sapD:Quickview

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

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Standard Name

sapD

Gene Synonym(s)

ECK1286, b1291, JW1284, trkE[1], trkE

Product Desc.

SapD[2][3];

Component of peptide uptake ABC transporter[2][3]

Required for ATP-dependence of Trk K+ uptake systems; putative ABC transport system ATP-binding protein; unknown substrate(s);[4]

Product Synonyms(s)

predicted antimicrobial peptide transporter subunit[1], ATP-binding component of ABC superfamily[1], B1291[2][1], TrkE[2][1], SapD[2][1] , ECK1286, JW1284, trkE, b1291

Function from GO

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Knock-Out Phenotype
Regulation/Expression

transcription unit(s): sapF[2]

Regulation/Activity
Quick Links

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Notes

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Overexpression causes filamentous biofilm formation. SapD(TrkE) is required for TrkAH activity and stimulates TrkAG transport rate (Bossemeyer, 1989; Dosch, 1991; Harms, 2001). Characterized initially in Salmonella. The proposal that the sap operon transports peptides (Groisman, 1992) has been challenged (Stumpe, 1997; Harms, 2001). SapA ATP-binding, but not hydrolysis, is required for stimulation of Trk (Harms, 2001).[4]



References

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  1. 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.