queA:Quickview
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Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
References | Suggestions |
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Standard Name |
queA |
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Gene Synonym(s) |
ECK0399, b0405, JW0395, tsaA[1] |
Product Desc. |
S-adenosylmethionine:tRNA ribosyltransferase-isomerase; queuosine biosynthesis,[4] |
Product Synonyms(s) |
S-adenosylmethionine:tRNA ribosyltransferase-isomerase[1], B0405[2][1], TsaA[2][1], QueA[2][1] , ECK0399, JW0395, b0405 |
Function from GO |
<GO_nr /> |
Knock-Out Phenotype | |
Regulation/Expression | |
Regulation/Activity | |
Quick Links | |
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Notes
Asn, Asp, Tyr, and His tRNA anticodons are modified. QueA converts 7-deazaguanine (preQ1-tRNA) to epoxyqueuosine (oQ-tRNA) in the penultimate step of Q-tRNA biosynthesis. The final step to make Q-tRNA from oQ-tRNA may be a cobamide-dependent reduction, but the gene is unknown (Frey, 1988). tgt mutants lack queuosine and are have reduced survival in stationary phase. (Noguchi, 1982).[4]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.