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Standard Name


Gene Synonym(s)

ECK2696, b2701, JW2671[1], JW2671

Product Desc.

membrane-bound lytic murein transglycosylase B[2][3]

Membrane-bound lytic transglycosylase B, murein hydrolase; periplasmic OM-attached lipoprotein; Slt35, soluble lytic transglycosylase[4]

Product Synonyms(s)

membrane-bound lytic murein transglycosylase B[1], B2701[2][1], MltB[2][1] , ECK2696, JW2671, b2701

Function from GO

<GO_nr />

Knock-Out Phenotype

transcription unit(s): mltB[2]

Quick Links

porteco.png EcoCyc.gif regulondb.jpg

dnadisplay.png proteindisplay.png   pubmed.jpg   textpresso.jpg  

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MltB cleaves the glycosidic bonds between the N-acetylmuramic acid and N-acetylglucosamine residues in murein. Slt35 is a soluble form of MltB with the lipid-anchored N-terminus cleaved after Phe39 during purification. The N-terminus of Slt35 has been identified by protein sequencing, but Slt35 is is an artifact of proteolysis during purification. First 18 aa are a type II signal peptide.[4]


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  1. 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.