mdtC:Quickview
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
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| Standard Name |
mdtC |
|---|---|
| Gene Synonym(s) |
ECK2072, b2076, JW2061, yegO[1], yegO |
| Product Desc. |
Component of MdtABC RND-type Drug Exporter[2]; MdtABC-TolC Multidrug Efflux Transport System[3] MdtABC-TolC efflux pump, multidrug resistance; heterodimeric RND-type transporter[4] |
| Product Synonyms(s) |
multidrug efflux system, subunit C[1], B2076[2][1], MdtC[2][1], YegO[2][1] , ECK2072, JW2061, yegO, b2076 |
| Function from GO |
<GO_nr /> |
| Knock-Out Phenotype | |
| Regulation/Expression |
transcription unit(s): mdtABCD-baeSR[2] |
| Regulation/Activity | |
| Quick Links |
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| edit table |
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Notes
mdtABC overexpression confers resistance to deoxycholate and novobiocin. An mdtABC mutant is not sensitive to deoxycholate and Nov. Upregulated by GSNO in defined medium (aerobic). BaeSR, EvgAS regulons.[4]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
