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References Suggestions


Standard Name


Gene Synonym(s)

ECK0354, b0357, JW0348, yaiN[1], yaiN

Product Desc.

regulator protein[2][3]

Negative regulator of the frmRAB operon[4]

Product Synonyms(s)

regulator protein that represses frmRAB operon[1], B0357[2][1], YaiN[2][1], FrmR[2][1] , ECK0354, JW0348, yaiN, b0357

Function from GO

<GO_nr />

Knock-Out Phenotype

transcription unit(s): frmB[2]

Quick Links

porteco.png EcoCyc.gif regulondb.jpg

dnadisplay.png proteindisplay.png   pubmed.jpg   textpresso.jpg  

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The frmRAB operon is negatively regulated by frmR, is induced by formaldehyde, and probably degrades formaldehyde. An amber suppressor allows readthrough of frmR, adding 7 aa, which inactivates FrmR, causing stimulation of frmRAB transcription. frmR and rcnR are paralogs.[4]


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  1. 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.